1838-56-8 Usage
Description
3-Hydroxy-2-acetylaminofluorene is a chemical compound that is a reactive metabolite of 2-acetylaminofluorene. It is known to mediate the increase in gene transcription and expression and is classified as a carcinogen.
Uses
Used in Research Applications:
3-Hydroxy-2-acetylaminofluorene is used as a research tool for studying the mechanisms of carcinogenesis and the effects of carcinogens on gene expression. Its ability to increase gene transcription and expression makes it a valuable compound for understanding the molecular pathways involved in cancer development.
Used in Toxicology Studies:
As a known carcinogen, 3-hydroxy-2-acetylaminofluorene is utilized in toxicology studies to investigate the potential health risks and effects of exposure to carcinogenic compounds. This helps in the development of safety guidelines and regulations to minimize the risk of cancer in humans and the environment.
Used in Drug Development:
3-Hydroxy-2-acetylaminofluorene may also be used in drug development to identify potential therapeutic agents that can counteract or mitigate the effects of carcinogens on gene expression and cellular processes. This can contribute to the discovery of new drugs for cancer prevention and treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1838-56-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,3 and 8 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1838-56:
(6*1)+(5*8)+(4*3)+(3*8)+(2*5)+(1*6)=98
98 % 10 = 8
So 1838-56-8 is a valid CAS Registry Number.
InChI:InChI=1/C15H13NO2/c1-9(17)16-14-7-11-6-10-4-2-3-5-12(10)13(11)8-15(14)18/h2-5,7-8,18H,6H2,1H3,(H,16,17)
1838-56-8Relevant articles and documents
Nucleophilic Aromatic Substitution on Ester Derivatives of Carcinogenic N-Arylhydroxamic Acids by Aniline and N,N-Dimethylaniline
Novak, Michael,Rangappa, Kanchugarakoppal S.,Manitsas, Rebecca K.
, p. 7813 - 7821 (2007/10/02)
Decomposition of N-(pivaloyloxy)-2-(acetylamino)fluorene (1b) and N-(sulfonatooxy)-4-(acetylamino)biphenyl (2a) in MeOH occurs predominately via N-O bond cleavage to yield oxazoles (5, 6, 23), methoxy adducts (7, 8, 24, 25, 26), and rearrangement products
