183859-36-1Relevant articles and documents
Chemoenzymatic approach to enantiopure piperidine-based β-amino esters in organic solvents
Liljeblad, Arto,Kavenius, Hanna-Maija,Taehtinen, Petri,Kanerva, Liisa T.
, p. 181 - 191 (2007/10/03)
This research concentrates on the enantioselectivities of lipase-catalysed reactions with methyl esters of 2-piperidylacetic acid and 3-piperidinecarboxylic acid derivatives. N-Acetylated 2-piperidylacetic acid methyl ester displayed good enantioselectivi
Enzymatic resolution of cyclic N-Boc protected β-aminoacids
Pousset, Cyrille,Callens, Roland,Haddad, Mansour,Larcheveque, Marc
, p. 3407 - 3412 (2007/10/03)
Methyl and ethyl esters of N-Boc homoproline, homopipecolic acid and 3-carboxymethyl-morpholine were kinetically resolved by hydrolysis catalysed by Burkholderia cepacia lipase to give the corresponding acids and residual esters in enantiomeric excesses better than 99% (E > 100).
Antagonists of gonadotropin releasing hormone
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, (2008/06/13)
PCT No. PCT/US97/08428 Sec. 371 Date Nov. 12, 1998 Sec. 102(e) Date Nov. 12, 1998 PCT Filed May 16, 1997 PCT Pub. No. WO97/44037 PCT Pub. Date Nov. 27, 1997There are disclosed compounds of formula (I) and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related conditions in both men and women.