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184036-34-8

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184036-34-8 Usage

Description

N-(4-chloro-3-methyl-oxazol-5-yl)-2-[2-(6-methylbenzo[1,3]dioxol-5-yl)acetyl]-thiophene-3-sulfonamide is a complex organic compound with a unique chemical structure. It is characterized by the presence of a thiophene-3-sulfonamide group, an oxazol-5-yl group, and a benzo[1,3]dioxol-5-yl acetyl group. N(4chloro3methyloxazol5yl)2[2(6methylbenzo[1,3]dioxol5yl)acetyl]thiophene3sulfonamide is likely to have various applications in different industries due to its diverse functional groups and chemical properties.

Uses

Used in Pharmaceutical Industry:
N-(4-chloro-3-methyl-oxazol-5-yl)-2-[2-(6-methylbenzo[1,3]dioxol-5-yl)acetyl]-thiophene-3-sulfonamide is used as a pharmaceutical compound for the development of new drugs. Its unique chemical structure and functional groups make it a promising candidate for targeting specific biological pathways and receptors, potentially leading to the development of novel therapeutic agents.
Used in Chemical Research:
N(4chloro3methyloxazol5yl)2[2(6methylbenzo[1,3]dioxol5yl)acetyl]thiophene3sulfonamide is also used in chemical research as a starting material or intermediate for the synthesis of other complex organic molecules. Its diverse functional groups and chemical properties make it a valuable tool for exploring new reaction pathways and developing innovative synthetic methods.
Used in Material Science:
N-(4-chloro-3-methyl-oxazol-5-yl)-2-[2-(6-methylbenzo[1,3]dioxol-5-yl)acetyl]-thiophene-3-sulfonamide may have potential applications in the field of material science, particularly in the development of new materials with specific properties. Its unique chemical structure could be utilized to create materials with tailored characteristics, such as improved stability, enhanced reactivity, or novel optical or electronic properties.

Originator

Encysive (US)

Check Digit Verification of cas no

The CAS Registry Mumber 184036-34-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,0,3 and 6 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 184036-34:
(8*1)+(7*8)+(6*4)+(5*0)+(4*3)+(3*6)+(2*3)+(1*4)=128
128 % 10 = 8
So 184036-34-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H17ClN2O6S2/c1-10-5-13-14(27-9-26-13)7-11(10)6-12(22)16-15(3-4-28-16)29(23,24)20-18-17(19)21(2)8-25-18/h3-5,7,20H,6,8-9H2,1-2H3

184036-34-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name N-(4-Chloro-3-methylisoxazol-5-yl)-2-(2-(6-methylbenzo-[d][1,3]dioxol-5-yl)acetyl)thiophene-3-sulfonamide

1.2 Other means of identification

Product number -
Other names Sitaxsentan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:184036-34-8 SDS

184036-34-8Downstream Products

184036-34-8Relevant articles and documents

METHODS AN COMPOSITIONS FOR TREATMENT OF AN INTERSTITIAL LUNG DISEASE

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Page/Page column 39-40, (2008/12/07)

Provided herein are methods of treatment of an interstitial lung disease (ILD) by administering an endothelin antagonist, such as sitaxsentan or a pharmaceutically acceptable salt thereof.

Formulations of sitaxsentan sodium

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Page/Page column 11, (2008/06/13)

Provided herein are stable lyophilized and oral formulations of sitaxsentan sodium. In certain embodiments the lyophilized formulations provided herein have improved stability upon reconstitution. Also provided are methods of making and using the formulations.

PROCESSES FOR THE PREPARATION OF 4-CHLORO-3-METHYL-5-(2-(2-(6-METHYLBENZO[D][1,3]DIOXOL-5-YL)ACETYL)-3-THIENYLSULFONAMIDO) ISOXAZOLE

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Page/Page column 12, (2008/06/13)

Provided are processes for the preparation of 4-chloro-3-methyl-5-(2-(2-(6- methylbenzo[d][1,3Jdioxol-5-yl)acetyl)-3-thienylsulfonamido)isoxazole of formula (I), a compound useful for the treatment of endothelin-mediated disorders.

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