1843-21-6

Basic information

• Product Name: N-PHENYL-1,3-BENZOTHIAZOL-2-AMINE
• Synonyms: 2-Anilinobenzothiazole;N-Phenyl-2-benzothiazolamine;N-Phenylbenzothiazole-2-amine;1,3-benzothiazol-2-yl(phenyl)amine
• CAS NO: 1843-21-6
• Molecular Formula: C₁₃H₁₀N₂S
• Molecular Weight: 226.3
• Mol File: 1843-21-6.mol
• Article Data: 77

Chemical Properties

• Boiling Point: 374.5°Cat760mmHg
• Flash Point: 180.3°C
• Appearance: /
• Density: 1.313g/cm³
• Vapor Pressure: 8.32E-06mmHg at 25°C
• Refractive Index: 1.746
• CAS DataBase Reference: N-PHENYL-1,3-BENZOTHIAZOL-2-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-PHENYL-1,3-BENZOTHIAZOL-2-AMINE(1843-21-6)
• EPA Substance Registry System: N-PHENYL-1,3-BENZOTHIAZOL-2-AMINE(1843-21-6)

Safety Data

• Hazardous Substances Data: 1843-21-6(Hazardous Substances Data)

Usage

General Description

N-PHENYL-1,3-BENZOTHIAZOL-2-AMINE, also known as aminobenzothiazole, is a chemical compound with the molecular formula C13H10N2S. It is a yellow to light brown crystalline solid that is commonly used as a rubber antioxidant and ultraviolet stabilizer in the production of rubber products. N-PHENYL-1,3-BENZOTHIAZOL-2-AMINE is also used as an intermediate in the synthesis of various dyes, pharmaceuticals, and agrochemicals. It has been found to have potential carcinogenic and mutagenic properties and should be handled with care and in accordance with safety regulations.

InChI:InChI=1/C13H10N2S/c1-2-6-10(7-3-1)14-13-15-11-8-4-5-9-12(11)16-13/h1-9H,(H,14,15)

Upstream product

• 103-72-0 phenyl isothiocyanate 
• 1227476-15-4 Azobenzene 
• 1141-88-4 2-Aminophenyl disulfide 
• 121-69-7 N,N-dimethyl-aniline 
• 102-02-3 1-phenylbiguanide 
• 67-66-3 chloroform 
• 7782-50-5 chlorine 
• 102-08-9 N,N-diphenylthiourea 
• 71-43-2 benzene 
• 705-62-4 N,N-dimethyl-N'-phenylthiourea 
• 62-53-3 aniline 
• 103-85-5 monophenylthiourea 
• 621-01-2 N,N'-Bis(p-tolyl)thiourea 
• 1145-66-0 1-(4-methylphenyl)-3-phenylthiourea 

Downstream Products

• 76402-03-4 2-N-phenyl-N-(phenylamino-phenyliminomethyl)aminobenzothiazole 
• 5401-29-6 N-benzothiazol-2-yl-N-phenyl-acetamide 
• 65416-74-2 3-methyl-2-phenylimino-2,3-dihydrobenzothiazole 
• 78072-94-3 N-methyl-N-phenylbenzo[d]thiazol-2-amine 
• 149-30-4 2-thioxo-3H-1,3-benzothiazole 
• 29483-73-6 2-(2-aminophenyl)benzthiazole 
• 26946-76-9 (6-nitro-benzothiazol-2-yl)-(4-nitro-phenyl)-amine 
• 56950-40-4 benzothiazol-2-yl-phenyl-thiocarbamoyl chloride 
• 27655-35-2 1-benzothiazol-2-yl-1,3-diphenyl-urea 
• 56950-42-6 1,3-bis-benzothiazol-2-yl-1,3-diphenyl-thiourea 
• 107470-37-1 1-Phenoxy-3-{2-[(Z)-phenylimino]-benzothiazol-3-yl}-propan-2-ol 
• 16954-69-1 2-methylaminobenzthiazole 
• 62-53-3 aniline 
• 1426925-72-5 tert-butyl 2,2′,2″-(10-(2-(4-(benzo[d]thiazol-2-yl)phenylamino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetate 

Relevant articles and documents

Synthesis of 4-substituted imino-4H-benzo[d][1,3] thiazin-2-amines via palladium-catalysed isocyanide insertion in 2-bromophenylthioureas

The palladium-catalysed isocyanide insertion in 2-bromophenylthioureas results in the formation of 4-substituted imino-4H-benzo[d][1,3]thiazin-2-amines via C-S cross coupling reaction of the intermediate imidoylpalladium species. The investigations into t

A Synthesis of Benzothiazoles and Indoles by Direct C(sp2)-I Activation Catalyzed by Copper(II) on Silica-Coated Magnetite Nanoparticles

N-Substituted 2-amino-1,3-benzothiazoles and 2,3-disubstituted indoles were prepared by C-S and C-C cross-coupling reactions of 2-iodoanilines with isothiocyanates or 1,3-dicarbonyl compounds, respectively, in the presence of magnetic nanoparticles functionalized with a copper(II)-Schiff base complex as an efficient and reusable catalyst.

Ruthenium catalyzed intramolecular C-S coupling reactions: Synthetic scope and mechanistic insight

A ruthenium catalyzed intramolecular C-S coupling reaction of N-arylthioureas for the synthesis of 2-aminobenzothiazoles has been developed. Kinetic, isotope labeling, and computational studies reveal the involvement of an electrophilic ruthenation pathwa

Ionic Reactivity of 2-Isocyanoaryl Thioethers: Access to 2-Halo and 2-Aminobenzothia/Selenazoles

An ionic cascade insertion/cyclization reaction of thia-/selena-functionalized arylisocyanides has been successfully developed for the efficient and practical synthesis of 2-halobenzothiazole/benzoselenazole derivatives. This synthetic protocol, incorporating a halogen atom when forming the five-membered ring of benzothia/selenazoles, is different from the existing ones, where halogenation of the preformed benzothia/selenazole precursors happens. Additionally, a facile access to 2-aminobenzothiazoles is also achieved by the one-pot cascade reaction of 2-isocyanoaryl thioethers, iodine, and amines.

Microwave-assisted hydrogen peroxide-mediated synthesis of benzoxazoles and related heterocycles via cyclodesulfurization

A novel approach has been developed to construct benzoxazoles and similar N- and S-containing heterocycles from their corresponding isothiocyanates and o-substituted anilines via cyclodesulfurization. The reaction was found to proceed via in situ formatio