184637-11-4 Usage
General Description
6-Bromo-1-(tert-butyldimethylsilyl)indole is a chemical compound with the molecular formula C18H24BrNSi. It is a derivative of indole, a heterocyclic aromatic organic compound, and contains a bromine atom and a tert-butyldimethylsilyl functional group. 6-Bromo-1-(tert-butyldimethylsilyl)indole is commonly used in organic synthesis as a building block for the preparation of various biologically active molecules and pharmaceuticals. The tert-butyldimethylsilyl group provides protection for reactive functional groups during synthetic reactions, allowing for selective modifications of the molecule. Additionally, the bromine atom can serve as a site for further chemical modifications and substitutions. Overall, 6-Bromo-1-(tert-butyldimethylsilyl)indole is a versatile compound with potential applications in medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 184637-11-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,4,6,3 and 7 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 184637-11:
(8*1)+(7*8)+(6*4)+(5*6)+(4*3)+(3*7)+(2*1)+(1*1)=154
154 % 10 = 4
So 184637-11-4 is a valid CAS Registry Number.
184637-11-4Relevant articles and documents
Rhodium-catalyzed C–H functionalization of heteroarenes using indoleBX hypervalent iodine reagents
Grenet, Erwann,Das, Ashis,Caramenti, Paola,Waser, Jér?me
supporting information, p. 1208 - 1214 (2018/06/04)
The C–H indolation of heteroarenes was realized using the benziodoxolone hypervalent iodine reagents indoleBXs. Functionalization of the C–H bond in bipyridinones and quinoline N-oxides catalyzed by a rhodium complex allowed to incorporate indole rings into aza-heteroaromatic compounds. These new transformations displayed complete regioselectivity for the C-6 position of bipyridinones and the C-8 position of quinoline N-oxides and tolerated a broad range of functionalities, such as halogens, ethers, or trifluoromethyl groups.
Novel small molecule compounds, preparation method thereof and method for treating/preventing HIV-1 infected aids by using compound
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Paragraph 0048, (2017/09/26)
The invention provides novel small molecule compounds inhibiting HIV, especially HIV-1 virus infection, a preparation method thereof and a method for inhibiting HIV, especially HIV-1 virus infection, to treat/prevent aids and relevant diseases by using th