18480-23-4

Basic information

• Product Name: Allyl triphenylphosphonium chloride
• Synonyms: ALLYL TRIPHENYLPHOSPHONIUM CHLORIDE;Phosphonium, triphenyl-2-propenyl-, chloride;Ally triphenyl phosphonium chloride;Allyl triphenylphosphonium chloride,97%;Triphenyl-allyl-phosphonium chloride
• CAS NO: 18480-23-4
• Molecular Formula: C₂₁H₂₀P*Cl
• Molecular Weight: 338.81
• EINECS: 242-368-7
• Product Categories: Phosphonium Compounds;Synthetic Organic Chemistry;Wittig & Horner-Emmons Reaction;Wittig Reaction
• Mol File: 18480-23-4.mol
• Article Data: 2

Chemical Properties

• Melting Point: 227-229 °C
• Appearance: Beige/Crystalline Powder
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive: Hygroscopic
• CAS DataBase Reference: Allyl triphenylphosphonium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Allyl triphenylphosphonium chloride(18480-23-4)
• EPA Substance Registry System: Allyl triphenylphosphonium chloride(18480-23-4)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-37/39
• WGK Germany: 3
• F: 3-10
• Hazardous Substances Data: 18480-23-4(Hazardous Substances Data)

Usage

Chemical Properties

Beige crystalline powder

InChI:InChI=1/C21H20P.ClH/c1-2-18-22(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21;/h2-17H,1,18H2;1H/q+1;/p-1

Upstream product

• 612-62-4 2-Chloroquinoline 
• 15935-94-1 allylidenetriphenylphosphorane 
• 603-35-0 triphenylphosphine 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 541508-16-1 (3aR,5R,6R,6aR)-6-Benzyloxy-5-((E)-buta-1,3-dienyl)-2,2-dimethyl-6-((E)-4-methyl-penta-2,4-dienyl)-tetrahydro-furo[2,3-d][1,3]dioxole 
• 541508-14-9 (3aR,5R,6R,6aR)-6-Benzyloxy-5-((E)-buta-1,3-dienyl)-2,2-dimethyl-6-((E)-penta-2,4-dienyl)-tetrahydro-furo[2,3-d][1,3]dioxole 
• 35044-57-6 ethyl 2,6,6-trimethyl-2,4-cyclohexadiene-1-carboxylate 
• 112031-81-9 5-methoxycarbonylpenta-2,4-dienylidenetriphenylphosphorane 
• 97478-20-1 cis-2-(1,3-butadienyl)-3-methyl-1-tosylaziridine 
• 15935-94-1 allylidenetriphenylphosphorane 
• 139166-39-5 Acetic acid 2-prop-2-en-(E)-ylidene-cyclohexyl ester 
• 54826-11-8 phenyltriene 
• 35044-56-5 (propenyl)triphenylphosphonium chloride 
• 1002-35-3 octa-1,3,7-triene 
• 83299-50-7 {(C₆H₅)3PC₃H₅}⁽¹⁺⁾*{FeCl₄}^(1-)={(C₆H₅)3PC₃H₅}{FeCl₄} 

Relevant articles and documents

2 - ((4R, 6S) - 6-triphenylphosphine alkene methylene base -2,2-di-substituted -1,3-dioxane-4-yl) acetate and its preparation method and application

The invention relates to a 2-((4R,6S)-6-triphenylphosphoalkenylmethylene-2,2-disubstituted-1,3-dioxyhexacyclo-4-yl)acetate, and a preparation method and application thereof. The method comprises the following steps: reacting 3-halopropylene and triphenylphosphine to generate allyltriphenyl halophosphine, and directly reacting with 3,3-dialkoxypropionate or 3-alkoxyacrylate under the catalytic action of Lewis acid by a one-pot process to prepare the target compound. The stable form of the hexatomic ring chair-structure equatorial bond is utilized to construct the chiral center without using any additional chiral assistant. The method has the advantages of accessible raw materials and short reaction procedure. The product containing the triphenylphosphine structure is easy to crystallize and purify, can be directly used for preparing rosuvastatin calcium, and can also be used for preparing the open-ring compound (3R,5S)-6-triphenylphosphoalkenyl-3.5-dihydroxy hexanoate.