1849-29-2 Usage
Description
Methanol-d3, also known as CD3OD or deuterated methanol, is a deuterated version of methanol where the hydrogen atoms are replaced by deuterium atoms. It is a clear, colorless liquid that is commonly used in nuclear magnetic resonance (NMR) spectroscopy due to its unique properties.
Uses
Used in NMR Spectroscopy:
Methanol-d3 is used as a solvent for various applications in NMR spectroscopy, particularly for the study of organic compounds. The deuterium atoms in methanol-d3 provide a non-reactive and non-exchangeable environment, which helps in reducing spectral complexity and improving the resolution of NMR signals.
Used in Chemical Synthesis:
Methanol-d3 is used as a reagent in the preparation of specific compounds for spectroscopic analysis. For example, it may be used in the preparation of [Al(CH3)2OCD3]3 by reacting with trimethylaluminum. METHANOL-D3 is useful for studying the structural and dynamic properties of dialkylaluminum alkoxides and the trialkylaluminum-ether complex.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, methanol-d3 can be employed as a solvent for the synthesis of deuterated drug molecules. These deuterated compounds can exhibit improved pharmacokinetic properties, such as enhanced stability, reduced metabolism, and increased bioavailability, which can lead to better therapeutic outcomes.
Used in Environmental Research:
Methanol-d3 can be utilized in environmental research for the study of trace organic contaminants in water and soil samples. The use of deuterated methanol as a solvent can help in the identification and quantification of these contaminants, providing valuable insights into their environmental impact and potential risks to human health.
Used in Material Science:
In material science, methanol-d3 can be employed as a solvent for the preparation and characterization of deuterated materials. These materials can exhibit unique properties, such as altered electronic or magnetic behavior, which can be useful for the development of advanced materials with specific applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 1849-29-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,8,4 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1849-29:
(6*1)+(5*8)+(4*4)+(3*9)+(2*2)+(1*9)=102
102 % 10 = 2
So 1849-29-2 is a valid CAS Registry Number.
InChI:InChI=1/CH4O/c1-2/h2H,1H3/i1D3
1849-29-2Relevant articles and documents
Oxyfunctionalization with CpIrIII(NHC)(Me)L complexes
Lehman, Matthew C.,Boyle, Paul D.,Sommer, Roger D.,Ison, Elon A.
, p. 5081 - 5084 (2014)
A series of monomethyl CpIrIII complexes were synthesized and studied for the formation of methanol in water. Methanol yields of 75(4)% in the presence of O2 were obtained. From isotope labeling studies, it was determined that O2 is the source of the oxygen atom in the product. From kinetic studies, oxyfunctionalization appears to proceed by dissociation of an L-type ligand followed by O2 binding and insertion.
Shiner
, p. 240,242 (1961)
Kice,Walters
, p. 590 (1972)
METHOD FOR PRODUCING DEUTERATED METHYL METHACRYLATE
-
Page/Page column 7, (2008/06/13)
A method for producing MMA-d8 which includes a step of exchanging D in hydroxyl group of methanol-d4 represented by the formula: CD3OD with H to prepare the methanol-d3 represented by the formula CD3OH and simultaneously recovering a deuterium-containing compound, and a step of reacting methanol-d3 with sulfuric acid salt of methacrylic acid amide represented by the formula CD2=(CD3)CO(NH2·H2SO4) to prepare MMA-d8 represented by the formula: CD2=(CD3)COOCD3.
Unusual ionic hydrogen bonds: Complexes of acetylides and fluoroform
Chabinyc, Michael L.,Brauman, John I.
, p. 8739 - 8745 (2007/10/03)
Ion-molecule complexes of substituted acetylides, RCC- (R = tert-butyl, H, phenyl, p-tolyl), and fluoroform, HCF3, were studied using Fourier transform ion cyclotron resonance mass spectrometry. These complexes, RCC-·HCF3, all have complexation energies of approximately -19 kcal/mol and are, therefore, hydrogen bonded. The acetylides vary in basicity over a 6 kcal/mol range, but all have the same complexation energy with fluoroform. The structure of these complexes was verified by deuterium isotopic exchange reactions and equilibrium fractionation experiments. The relationship between acid-base thermochemistry and hydrogen bond stability is discussed.
