18523-15-4

Basic information

• Product Name: 1,3,5-TRIMETHOXY-2,4-DINITROBENZENE
• Synonyms: 1,3,5-TRIMETHOXY-2,4-DINITROBENZENE;2,4-DINITRO-1,3,5-TRIMETHOXYBENZENE
• CAS NO: 18523-15-4
• Molecular Formula: C₉H₁₀N₂O₇
• Molecular Weight: 258.18
• Mol File: 18523-15-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 443.3°Cat760mmHg
• Flash Point: 213.9°C
• Appearance: /
• Density: 1.394g/cm³
• Vapor Pressure: 1.23E-07mmHg at 25°C
• Refractive Index: 1.554
• CAS DataBase Reference: 1,3,5-TRIMETHOXY-2,4-DINITROBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,5-TRIMETHOXY-2,4-DINITROBENZENE(18523-15-4)
• EPA Substance Registry System: 1,3,5-TRIMETHOXY-2,4-DINITROBENZENE(18523-15-4)

Safety Data

• Hazardous Substances Data: 18523-15-4(Hazardous Substances Data)

Usage

Appearance

Pale yellow crystalline solid

Primary use

Reagent in organic synthesis

Reactivity

Highly reactive

Derivatives

Used in the preparation of various derivatives for other chemical processes

Analytical chemistry

Used as a reagent for the analysis of various substances

Potential medical applications

Investigated for its potential use in the treatment of various diseases (still under study)

Applications

Wide range of applications in organic synthesis and analytical chemistry

InChI:InChI=1/C9H10N2O7/c1-16-5-4-6(17-2)8(11(14)15)9(18-3)7(5)10(12)13/h4H,1-3H3

Upstream product

• 51686-79-4 2,4,6-tribromo-1,3-dinitrobenzene 
• 124-41-4 sodium methylate 
• 14227-18-0 1,3,5-trimethoxy-2-nitrobenzene 
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• 108-24-7 acetic anhydride 
• 832-58-6 1-(2,4,6-trimethoxyphenyl)ethanone 
• 7539-25-5 1-methoxy-2,3,5-trinitrobenzene 
• 18708-70-8 2,4,6-trichloronitrobenzene 
• 861548-13-2 1,5-dimethoxy-2,3-dinitro-benzene 
• 16147-07-2 1,3-dimethoxy-5-nitrobenzene 
• 5327-44-6 3,5-dinitroanisole 
• 6284-83-9 1,3,5-trichloro-2,4-dinitrobenzene 
• 71-43-2 benzene 
• 54234-85-4 2,4-dinitro-phloroglucinol 

Downstream Products

• 129612-04-0 2-amino-4-nitro-1,3,5-trimethoxybenzene 

Relevant articles and documents

Electrophilic tetraalkylammonium nitrate nitration. II. Improved anhydrous aromatic and heteroaromatic mononitration with tetramethylammonium nitrate and triflic anhydride, including selected microwave examples

A new one-pot nitration employing tetramethylammonium nitrate and trifluoromethanesulfonic anhydride in dichloromethane to provide a ready source of the nitronium triflate nitrating agent is presented. Rapid and selective nitration with a variety of aromatic and heteroaromatic substrates is achieved resulting in the synthesis of several novel organic compounds. A distinct advantage is the removal of undesired byproducts by aqueous workup. This very mild nitration permits large-scale syntheses and gives high isolated product yields that often require no further purification. This tetramethylammonium nitrate-based nitration also has been applied to microwave-assisted conditions, and the results with several compounds are outlined.