185329-74-2

Basic information

• Product Name: 3-Thiophenemethanol, a-phenyl-, acetate
• CAS NO: 185329-74-2
• Molecular Formula: C13H12O2S
• Molecular Weight: 232.303
• Mol File: 185329-74-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-Thiophenemethanol, a-phenyl-, acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Thiophenemethanol, a-phenyl-, acetate(185329-74-2)
• EPA Substance Registry System: 3-Thiophenemethanol, a-phenyl-, acetate(185329-74-2)

Safety Data

• Hazardous Substances Data: 185329-74-2(Hazardous Substances Data)

Upstream product

• 27921-48-8 3-benzylthiophene 
• 64-19-7 acetic acid 
• 100-58-3 phenylmagnesium bromide 
• 498-62-4 3-thiophene carboxaldehyde 
• 102871-39-6 phenyl(thiophen-3-yl)methanol 
• 108-24-7 acetic anhydride 

Downstream Products

• 6453-99-2 3-benzoylthiophene 
• 27921-48-8 3-benzylthiophene 

Relevant articles and documents

Metal-Free Aerobic Oxidative C–O Coupling of C(sp3)–H with Carboxylic Acids Catalyzed by DDQ and tert-Butyl Nitrite

The formation of the C–O bond is one of the hot topics in the area of C(sp3)–H bond functionalization. A metal-free oxidative cross-coupling between benzylic C(sp3)–H bond and carboxylic acids has been developed. The reactions were performed with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) as the catalyst, tert-butyl nitrite (TBN) as the co-catalyst, and molecular oxygen as the terminal oxidant. A variety of diarylmethanes could be successfully coupled with various carboxylic acids to obtain diarylmethanol esters in good to excellent yields. In addition, 2-benzylbenzoic acids could be converted into phthalides in moderate yields through an intramolecular oxidative cyclization.