185389-91-7Relevant articles and documents
A concise synthesis of either enantiomer of azatyrosine
Cooper, Margaret S.,Seton, Alison W.,Stevens, Malcolm F. G.,Westwell, Andrew D.
, p. 2613 - 2616 (1996)
A facile route to either enantiomer of azatyrosine is reported, utilising an efficient enzymic resolution of protected azatyrosine ethyl ester by α-chymotrypsin as a key step.
A stereocontrolled synthesis of (R)- and (S)-azatyrosine
Cremonesi, Giuseppe,Dalla Croce, Piero,La Rosa, Concetta,Pizzatti, Enrica
, p. 563 - 567 (2007/10/03)
An asymmetric synthesis of (R)- or (S)- azatyrosine, starting from (2S)- or (2R)-2,5-dihydro-3,6-dimethoxy-2-isopropylpyrazine (5) (Scho?llkopf reagent) and 5-benzenesulfonyloxy-2-hydroxymethylpyridine (3), is reported. The diastereocontrolled addition gi
Enantioselective synthesis of (2-pyridyl)alanines via catalytic hydrogenation and application to the synthesis of L-azatyrosine.
Adamczyk,Akireddy,Reddy
, p. 3157 - 3159 (2007/10/03)
[reaction: see text] A novel method for the synthesis of (2-pyridyl)alanines 2a-b was developed by converting (2-pyridyl)dehydroamino acid derivatives 1a-b to the corresponding N-oxides 3a-b followed by asymmetric hydrogenation using (R,R)-[Rh(Et-DUPHOS)(