185413-30-3 Usage
Description
AF12198 is a peptide that selectively binds to the Interleukin-1 (IL-1) receptor, effectively blocking in vivo responses to IL-1. This interaction with the IL-1 receptor plays a crucial role in modulating the innate immune response, as the receptor can activate this response by binding to cytokines. The peptide's ability to regulate cytokine production helps prevent dysregulation, which could otherwise lead to auto-inflammatory disorders.
Uses
Used in Pharmaceutical Industry:
AF12198 is used as a therapeutic agent for the treatment of auto-inflammatory disorders. By selectively binding to the IL-1 receptor and blocking its response, AF12198 can help regulate cytokine production and prevent aberrant immune cell activation, thus mitigating the symptoms and progression of these disorders.
Used in Research Applications:
AF12198 is used as a research tool for studying the role of IL-1 and its receptor in immune response and inflammation. Its ability to selectively bind and block the IL-1 receptor makes it a valuable asset in understanding the underlying mechanisms of various immune-related conditions and potential therapeutic targets for treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 185413-30-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,5,4,1 and 3 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 185413-30:
(8*1)+(7*8)+(6*5)+(5*4)+(4*1)+(3*3)+(2*3)+(1*0)=133
133 % 10 = 3
So 185413-30-3 is a valid CAS Registry Number.
