185456-43-3Relevant articles and documents
Facile synthesis of mono-, di-, and trisubstituted alpha-unbranched hydrazines
Rasmussen, Lars K.
, p. 3627 - 3629 (2006)
Methods for the alkylation of di-tert-butyl hydrazine-1,2-dicarboxylate were investigated. It was found that under mild conditions mono- or di-substituted hydrazine derivatives were obtained in good to excellent yield. Furthermore, it was shown that one o
Convenient C(sp3)-H bond functionalisation of light alkanes and other compounds by iron photocatalysis
Duan, Chunying,Jin, Yunhe,Meng, Changgong,Wang, Lifang,Wang, Xinyao,Zhang, Qingqing
supporting information, p. 6984 - 6989 (2021/09/28)
Light alkanes are natural organic carbon sources and widely distributed in nature. Transforming them into value-added fine chemicals affords attractively economic and ecological benefits as well as enormous chemical challenges. Herein, we report a practical iron-catalysed photoredox system for C(sp3)-H transformation of ethane, propane, and other light alkanes to C-N and C-C bonds under ambient temperature. The present method with abundant and inexpensive iron salts as photocatalysts exhibits high catalytic efficiency (turnover number up to 8000), mild conditions, and the convenience of being purified and scaled up without chromatography. A photo-induced ligand-to-metal charge transfer between Fe(iii) and Cl- generates a highly active chlorine radical that sequentially acts as hydrogen atom transfer catalyst. Therefore, the sustainable, convenient, and environmentally friendly system will find wide applications in high-value-added transformation of natural alkanes with novel inspiration not only for organic synthesis, but also for designing catalytically active organic/inorganic materials. This journal is
Alkylation Reactions of Azodicarboxylate Esters with 4-Alkyl-1,4-Dihydropyridines under Catalyst-Free Conditions
Nakajima, Kazunari,Zhang, Yulin,Nishibayashi, Yoshiaki
supporting information, p. 4642 - 4645 (2019/06/17)
Introduction of alkyl groups on azodicarboxylate esters is an important method to prepare alkyl amine derivatives. Herein, we report reactions of 4-alkyl-1,4-dihydropyridines as alkylation reagents with di-tert-butyl azodicarboxylate to prepare alkyl amin
Synthesis of benzyl hydrazine derivatives: Via amination of benzylic C(sp3)-H bonds with dialkyl azodicarboxylates
Samzadeh-Kermani
, p. 4766 - 4772 (2018/03/21)
A novel synthesis of benzyl hydrazines through oxidative amination of benzylic C-H bonds has been developed. The resulting aminated products are accessed directly from the reaction of alkylarenes with dialkyl/diphenyl azodicarboxylates using Cu2O/Phen as the catalytic system. The reaction proceeded smoothly and a decent range of N-substituted hydrazides was synthesized in acceptable to good yields. Both primary and secondary sp3 C-H sources afford only monoamination products.