185461-12-5

Basic information

• Product Name: Phosphoric acid, diethyl 1-phenylpropyl ester, (R)-
• CAS NO: 185461-12-5
• Molecular Formula: C13H21O4P
• Molecular Weight: 272.281
• Mol File: 185461-12-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Phosphoric acid, diethyl 1-phenylpropyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphoric acid, diethyl 1-phenylpropyl ester, (R)-(185461-12-5)
• EPA Substance Registry System: Phosphoric acid, diethyl 1-phenylpropyl ester, (R)-(185461-12-5)

Safety Data

• Hazardous Substances Data: 185461-12-5(Hazardous Substances Data)

Upstream product

• 1565-74-8 (R)-1-phenyl-1-propanol 
• 814-49-3 diethyl chlorophosphate 

Relevant articles and documents

Deprotonation of secondary benzylic phosphates - configuratiionally stabite benzylic carbanions with a diethoxyphosphoryloxy substituent and their rearrangement to optically active tertiary α-hydroxyphosphonates

Optically active alcohols (ee ≥ 98%) such as 1-phenylpropanol, l-(2-naphthyl)ethanol, 1-tetralol, and 1-indanol were transformed into diethyl phosphates 7a-d. sBuLi/TMEDA -induced phosphate-phosphonate rearrangement in diethyl ether furnished tertiatry α-hydroxyphosphonates 8a-d of high enantiomeric purity (ee 94-98%) in yields of 43-83% with retention of configuration. The enantiomeric excesses were determined by using homochiral (-butyl(phenyl)phosphinothioic acid as chiral solvating agent. VCH Verlaiseesellschaft mbH, 1996.