185761-24-4

Basic information

• Product Name: (R)-2-(4-Chloro-phenyl)-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile
• Synonyms: (R)-2-(4-Chloro-phenyl)-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile
• CAS NO: 185761-24-4
• Molecular Weight: 310.783
• Mol File: 185761-24-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (R)-2-(4-Chloro-phenyl)-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2-(4-Chloro-phenyl)-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile(185761-24-4)
• EPA Substance Registry System: (R)-2-(4-Chloro-phenyl)-3-((R)-4-phenyl-4,5-dihydro-oxazol-2-yl)-propionitrile(185761-24-4)

Safety Data

• Hazardous Substances Data: 185761-24-4(Hazardous Substances Data)

Upstream product

• 185761-28-8 (E)-3-(4-Chloro-phenyl)-N-((R)-2-hydroxy-1-phenyl-ethyl)-acrylamide 
• 56613-80-0 D-2-phenylglycinol 
• 35086-79-4 cinnamoyl chloride 
• 5804-85-3 diethylaluminium cyanide 
• 185761-22-2 (4R)-2-[(E)-2-(p-chlorophenyl)ethenyl]-4-phenyl-4,5-dihydrooxazole 

Downstream Products

• 185761-27-7 (R)-2-[(R)-4-(4-Chloro-phenyl)-4,5-dihydro-3H-pyrrol-2-ylamino]-2-phenyl-ethanol 
• 69308-37-8 (R)-baclofen 

Relevant articles and documents

Enantioselective syntheses of (R)-3-phenyl GABA, (R)-baclofen and 4-arylpyrrolidin-2-ones

Enantioselective synthesis of (R)-4-amino-3-phenylbutyric acid and (R)-baclofen has been achieved through a diastereoselective conjugate addition of cyanide to enantiomerically pure 2-(2-arylethenyl)oxazolines, followed by chemoselective reduction into cyclic amidines.