185817-70-3Relevant articles and documents
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease
Arce, Mariana P.,Rodríguez-Franco, María Isabel,González-Mu?oz, Gema C.,Pérez, Concepción,López, Beatriz,Villarroya, Mercedes,López, Manuela G.,García, Antonio G.,Conde, Santiago
experimental part, p. 7249 - 7257 (2010/06/16)
Novel multifunctional compounds have been designed, synthesized, and evaluated as potential drugs for the treatment of Alzheimer's disease (AD). With an L-glutamic moiety as a suitable biocompatible linker, three pharmacophoric groups were joined: (1) anN