18592-06-8Relevant articles and documents
Pd-assisted cross-coupling reactions with 4-chlorocinnoline
Heiter, Helmut Julian,Vilkauskaite, Gyte,Holzer, Wolfgang
, p. 141 - 144 (2013/03/13)
A series of 4-ethynylcinnolines 3a-e was prepared by Sonogashira reaction of 4-chlorocinnoline (1) with appropriate alkynes. Moreover, Suzuki coupling of with boronic esters gave the corresponding 4-arylcinnolines 5a-c. Detailed NMR spectroscopic data including unambiguous chemical shift assignments of all 1H, 13C, and 15N resonances of the obtained cinnoline derivatives are reported.