186000-44-2 Usage
General Description
3-BROMOPHENYLZINC IODIDE is a chemical compound with the molecular formula C6H5BrZnI. It is an organozinc reagent used in organic synthesis as a source of the phenylzinc functional group. 3-BROMOPHENYLZINC IODIDE is commonly used in Grignard-type reactions to introduce the phenyl group into organic molecules. It is a valuable reagent in the field of organic chemistry for the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. 3-BROMOPHENYLZINC IODIDE is known for its ability to perform selective and efficient reactions, making it an important tool for synthetic chemists in the development of new compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 186000-44-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,0,0 and 0 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 186000-44:
(8*1)+(7*8)+(6*6)+(5*0)+(4*0)+(3*0)+(2*4)+(1*4)=112
112 % 10 = 2
So 186000-44-2 is a valid CAS Registry Number.
InChI:InChI=1/C6H4Br.HI.Zn/c7-6-4-2-1-3-5-6;;/h1-2,4-5H;1H;/q-1;;+2/p-1/rC6H4Br.IZn/c7-6-4-2-1-3-5-6;1-2/h1-2,4-5H;/q-1;+1
186000-44-2Relevant articles and documents
Nickel-Catalyzed α-Carbonylalkylarylation of Vinylarenes: Expedient Access to γ,γ-Diarylcarbonyl and Aryltetralone Derivatives
Dhungana, Roshan K.,Giri, Ramesh,Khanal, Namrata,Shekhar, K. C.
, p. 8047 - 8051 (2020)
We report a Ni-catalyzed regioselective α-carbonylalkylarylation of vinylarenes with α-halocarbonyl compounds and arylzinc reagents. The reaction works with primary, secondary, and tertiary α-halocarbonyl molecules, and electronically varied arylzinc reagents. The reaction generates γ,γ-diarylcarbonyl derivatives with α-secondary, tertiary, and quaternary carbon centers. The products can be readily converted to aryltetralones, including a precursor to Zoloft, an antidepressant drug.
