186143-62-4

Basic information

• Product Name: 1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol
• Synonyms: 1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol
• CAS NO: 186143-62-4
• Molecular Weight: 276.258
• Mol File: 186143-62-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol(186143-62-4)
• EPA Substance Registry System: 1,1-Diphenyl-4,4,4-trifluorobut-2-yn-1-ol(186143-62-4)

Safety Data

• Hazardous Substances Data: 186143-62-4(Hazardous Substances Data)

Upstream product

• 119-61-9 benzophenone 
• 1514-82-5 2-bromo-3,3,3-trifluoropropene 
• 943610-08-0 1,1-dichloro-3,3,3-trifluoro-2-tosyloxypropene 

Downstream Products

• 1037582-87-8 C₂₃H₁₈F₃N₃O 
• 1037582-89-0 C₂₄H₂₈F₃N₃O 
• 1225289-38-2 4,4,4-trifluoro-1,1-diphenyl-2-butyn-1-yl 2-propyn-1-yl ether 

Relevant articles and documents

2-Bromo-3,3,3-trifluoropropene: A facile trifluoromethylacetylene anion synthon

The introduction of trifluoromethylacetylene units into organic compounds has been further studied and extended. The direct reaction of two equivalents of Lithium Diisopropylamide with 2-bromo-3,3,3-trifluoropropene gave lithium trifluoromethylacetylide, the anion of which was trapped in greater than 90% overall yield with a variety of electrophiles.

Novel generation of 3,3,3-trifluoropropynyllithium and transformation of the carbonyl adducts to trifluoromethyl-substituted allenes

A novel method for the generation of 3,3,3-trifluoropropynyllithium is reported, which involves treatment of trifluoromethyl-substituted enol tosylate, prepared from 1,1-dichloro-3,3,3-trifluoroacetone, with two equivalents of butyllithium. Palladium-cata