186308-99-6

Basic information

• Product Name: Butanoic acid,2-amino-4-[[imino(methylamino)- methyl]amino]-,(2S)-
• Synonyms: Butanoic acid,2-amino-4-[[imino(methylamino)- methyl]amino]-,(2S)-;Nω-Methyl L-Norarginine;(2S)-2-AMino-4-[[iMino(MethylaMino)Methyl]aMino]butanoic Acid;4124W;Nω-Methyl-nor-L-Arginine
• CAS NO: 186308-99-6
• Molecular Formula: C6H14N4O2
• Molecular Weight: 174
• Product Categories: Amines;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 186308-99-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Butanoic acid,2-amino-4-[[imino(methylamino)- methyl]amino]-,(2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid,2-amino-4-[[imino(methylamino)- methyl]amino]-,(2S)-(186308-99-6)
• EPA Substance Registry System: Butanoic acid,2-amino-4-[[imino(methylamino)- methyl]amino]-,(2S)-(186308-99-6)

Safety Data

• Hazardous Substances Data: 186308-99-6(Hazardous Substances Data)

Usage

Description

Butanoic acid, 2-amino-4-[[imino(methylamino)-methyl]amino]-, (2S)is an L-Arginine derivative that plays a crucial role in the regulation of endogenous nitric oxide synthase (NOS) inhibitors. Butanoic acid,2-amino-4-[[imino(methylamino)methyl]amino]-,(2S) is characterized by its unique chemical structure, which allows it to inhibit the enzyme dimethylarginine dimethylaminohydrolase, responsible for metabolizing NG-monomethyl-L-arginine and NG,NG-dimethyl-L-arginine to citrulline.

Uses

Used in Pharmaceutical Industry:
Butanoic acid, 2-amino-4-[[imino(methylamino)-methyl]amino]-, (2S)is used as a therapeutic agent for the treatment of various medical conditions. Its primary application is in the inhibition of the enzyme dimethylarginine dimethylaminohydrolase, which is involved in the metabolism of endogenous nitric oxide synthase (NOS) inhibitors. By inhibiting this enzyme, the compound can potentially improve nitric oxide bioavailability, which is essential for various physiological processes, including vasodilation, immune response, and neurotransmission.
Used in Cardiovascular Applications:
In the cardiovascular field, Butanoic acid, 2-amino-4-[[imino(methylamino)-methyl]amino]-, (2S)is used as a therapeutic agent to improve endothelial function and reduce the risk of cardiovascular diseases. The compound's ability to inhibit the enzyme dimethylarginine dimethylaminohydrolase can lead to increased nitric oxide production, which is known to promote vasodilation and reduce blood pressure. This makes it a promising candidate for the treatment of hypertension and other related conditions.
Used in Neurological Applications:
Butanoic acid, 2-amino-4-[[imino(methylamino)-methyl]amino]-, (2S)is also used in the neurological field to enhance nitric oxide signaling, which is essential for various brain functions, including memory, learning, and synaptic plasticity. By inhibiting the enzyme dimethylarginine dimethylaminohydrolase, the compound can potentially improve cognitive function and protect against neurodegenerative diseases such as Alzheimer's and Parkinson's.
Used in Immunological Applications:
In the immunological field, Butanoic acid, 2-amino-4-[[imino(methylamino)-methyl]amino]-, (2S)is used as an immunomodulatory agent. Nitric oxide, which is regulated by the enzyme dimethylarginine dimethylaminohydrolase, plays a crucial role in the immune system, particularly in the regulation of inflammation and the defense against pathogens. By inhibiting this enzyme, the compound can potentially enhance the immune response and improve the body's ability to fight infections and other immune-related disorders.