186353-05-9 Usage
Description
[N-methyl-N-phenyl]carbamic acid chloromethyl ester, with the molecular formula C9H10NO2Cl, is a carbamate ester derived chemical compound. It features a carbamic acid group connected to a phenyl and a methyl group, with an additional chloromethyl group attached to the carbamic acid group. [N-methyl-N-phenyl]carbamic acid chloromethyl ester is recognized for its role in organic synthesis and its potent acetylcholinesterase inhibiting properties, which affect the neurotransmitter acetylcholine in the nervous system. However, it is also known for its toxicity and potential health risks, necessitating careful handling in laboratory environments.
Uses
Used in Organic Synthesis:
[N-methyl-N-phenyl]carbamic acid chloromethyl ester is utilized as a reagent in organic synthesis, specifically for the formation of amide bonds. Its unique structure allows it to facilitate crucial chemical reactions, making it a valuable component in this field.
Used in Pharmaceutical Research:
As a potent acetylcholinesterase inhibitor, [N-methyl-N-phenyl]carbamic acid chloromethyl ester is used in the research and development of drugs targeting the nervous system. Its ability to interfere with the breakdown of acetylcholine can have significant implications for the treatment of various neurological conditions.
Used in Laboratory Settings:
[N-methyl-N-phenyl]carbamic acid chloromethyl ester is also employed in laboratory settings for educational purposes and to conduct experiments related to its chemical properties and potential applications. However, due to its toxicity and potential health hazards, it must be handled with extreme care and under proper safety conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 186353-05-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,3,5 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 186353-05:
(8*1)+(7*8)+(6*6)+(5*3)+(4*5)+(3*3)+(2*0)+(1*5)=149
149 % 10 = 9
So 186353-05-9 is a valid CAS Registry Number.
186353-05-9Relevant articles and documents
N-substituted carbamoyloxyalkyl-azolium derivatives
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Page/Page column 32, (2010/02/09)
N-substituted carbamoyloxyalkyl-azolium derivatives which have antifungal activity and are useful for the treatment of fungal diseases.
α-Haloalkyl Haloformates and Related Compounds 3.1 A Facile Synthesis of Symmetrical and Unsymmetrical Ureas via Chloromethyl Carbamates
Patonay, Tamas,Patonay-Peli, Erzsebet,Zolnai, Laszlo,Mogyorodi, Ferenc
, p. 4253 - 4265 (2007/10/03)
Chloromethyl carbamates were prepared by the reaction of chloromethyl chloroformates with amines and found to produce mono-, symmetrically or unsymmetrically di- and trisubstituted ureas including their N-hydroxy and N-alkoxy derivatives in moderate to good yield.
