186366-21-2

Basic information

• Product Name: (5R,9R,10R)-(+)-drim-7-en-11-ol
• Synonyms: (5R,9R,10R)-(+)-drim-7-en-11-ol
• CAS NO: 186366-21-2
• Molecular Weight: 222.371
• Mol File: 186366-21-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (5R,9R,10R)-(+)-drim-7-en-11-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (5R,9R,10R)-(+)-drim-7-en-11-ol(186366-21-2)
• EPA Substance Registry System: (5R,9R,10R)-(+)-drim-7-en-11-ol(186366-21-2)

Safety Data

• Hazardous Substances Data: 186366-21-2(Hazardous Substances Data)

Downstream Products

• 293312-51-3 (11R,S)-11-(2',5'-di(tetrahydropyran-2-yloxy)-1'-phenyl)drim-7-en-11-ol 
• 293310-05-1 C₃₁H₄₆O₄ 
• 39707-59-0 isozonarone 
• 39707-55-6 (+)-isozonarol 

Relevant articles and documents

Superacidic cyclisation-lipase-mediated kinetic resolution as a short route from achiral linear isoprenoid alcohols to scalemic cyclic isomers

(±)-α-Cyclogeraniol and (±)-drim-7-en-11-ol acetates obtained via the FSO3H-induced cyclisation of geraniol and (E)-farnesol and subsequent acetylation were hydrolysed in the presence of hog pancreas lipase (PPL) to afford (R)-(+)-α-cyclogeraniol (ee ～30% at the optimal conversion C = 20±2%) and (5R,9R,10R)-(+)-drim-7-en-11-ol (ee 78.5% at C = 30%), respectively; (±)-15-acetoxyisoagath-12-ene, obtained similarly from all-E-geranylgeraniol, is resistant to PPL-mediated hydrolysis, but is hydrolysed in the presence of lipase from Candida cylindracea to afford (10S,14R)-(-)-isoagath-12-en-15-ol of 69-80% ee in ～3% yield.