18671-89-1

Basic information

• Product Name: ethyl 2-(4-chlorophenoxy)propanoate
• CAS NO: 18671-89-1
• Molecular Formula: C₁₁H₁₃ClO₃
• Molecular Weight: 228.6721
• Mol File: 18671-89-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 293.8°C at 760 mmHg
• Flash Point: 114.9°C
• Density: 1.171g/cm³
• Vapor Pressure: 0.00168mmHg at 25°C
• Refractive Index: 1.506
• CAS DataBase Reference: ethyl 2-(4-chlorophenoxy)propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-(4-chlorophenoxy)propanoate(18671-89-1)
• EPA Substance Registry System: ethyl 2-(4-chlorophenoxy)propanoate(18671-89-1)

Safety Data

• Hazardous Substances Data: 18671-89-1(Hazardous Substances Data)

Upstream product

• 106-48-9 4-chloro-phenol 
• 535-11-5 Ethyl 2-bromopropionate 
• 1193-00-6 sodium 4-chlorophenolate 
• 42412-84-0 ethyl 2-phenoxypropionate 
• 535-13-7 2-chloro-propanoic acid, ethyl ester 
• 7553-56-2 iodine 
• 7782-50-5 chlorine 
• 64-19-7 acetic acid 
• 1121-74-0 potassium 4-chlorophenoxide 

Downstream Products

• 92849-15-5 (+/-)-2-<4-Chlorphenoxy>-propionsaeure-<3-aminopropylamid> 
• 6738-86-9 (+/-)-2-<4-Chlorphenoxy>-propionsaeure-<3-dimethylaminopropylamid> 
• 6806-29-7 N,N-Diethyl-N'-<2-(4-chlor-phenoxy)-propionyl>-ethylendiamin 
• 63650-24-8 2-(4-chlorophenoxy)-1-propanol 
• 1434516-76-3 2-(4-chlorophenoxy)-N-(2-(pyridine-4-yl)benzo[d]oxazol-5-yl)propanamide 
• 3307-39-9 (S)-2-(4-chlorophenoxy)propionic acid 
• 3307-39-9 (R)-2-(4-chlorophenoxy)propanoic acid 
• 175442-03-2 2-(4-chlorophenoxy)propionaldehyde 
• 90299-71-1 2-(2-(4-chlorophenoxy)propionyl)-N-phenylhydrazine thioformamide 
• 90327-19-8 5-[1-(4-chloro-phenoxy)-ethyl]-4-phenyl-2,4-dihydro-[1,2,4]triazole-3-thione 
• 52094-96-9 2-(4-chlorophenoxy)propionyl hydrazide 
• 3307-39-9 2-(4-chlorophenoxy)propionic acid 

Relevant articles and documents

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Preparation method of chlorophenoxycarboxamide salt

The invention provides a preparation method of chlorophenoxycarboxamide salt, wherein the preparation method includes the following steps: S1) carrying out 2-site and/or 4-site selective chlorinationreaction of phenoxycarboxylic ester with a chlorinating agent under the action of a catalyst A and a catalyst B to obtain chlorophenoxycarboxylic ester, wherein the catalyst A is Lewis acid, and the catalyst B has the following structural formula of R1'-S-R2'; and S2) carrying out ammonolysis reaction of chlorophenoxycarboxylic ester and amine to obtain chlorophenoxycarboxamide salt. By redesigning of the process route and fine screening of the catalysts and the chlorinating agent, the method reduces energy consumption, improves chlorination selectivity and avoids loss of effective components.The yield of the obtained chlorophenoxycarboxamide salt can reach 98.5% or more. At the same time, the production of high-salt wastewater is completely eradicated, the dust hazard caused by drying and use of chlorophenoxycarboxylic acid is avoided, energy is saved and equipment investment is reduced.

Preparation method of chlorophenoxycarboxylic ester

The invention provides a preparation method of chlorophenoxycarboxylic ester, wherein the preparation method includes the following steps: S1) carrying out 2-site and/or 4-site selective chlorinationreaction of phenoxycarboxylic ester with a chlorinating agent under the action of a catalyst A and a catalyst B to obtain chlorophenoxycarboxylic ester, wherein the catalyst A is Lewis acid, the catalyst B is C5-22 thiazoles, isothiazoles and thiophenes or halogenated derivatives thereof, and the phenoxycarboxylic ester has any structure represented by the formulas I-IV; and S2) carrying out transesterification reaction of chlorophenoxycarboxylic ester and alcohol under the action of a catalyst to obtain long-chain chlorophenoxycarboxylic ester, wherein the alcohol has the molecular formula ofR2OH, and R2 is C4-20 alkyl or cycloalkyl. The method improves the yield and purity of chlorophenoxycarboxylic ester by redesigning of the process route and fine screening of the catalysts and the chlorinating agent. The content of the obtained chlorophenoxycarboxylic ester can reach 98.5% or more and the yield can reach 98.5% or more.