186772-43-0 Usage
Description
Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodo-, also known as a substituted benzene derivative, is a chemical compound with the molecular formula C10H12BrI. It features a bromo and iodo group attached to the third and fifth carbon atoms, respectively, and a 1,1-dimethylethyl group attached to the first carbon atom. Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodois commonly utilized in organic synthesis and serves as a reagent in various chemical reactions. Due to its potential health and safety hazards, it is crucial to handle Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodowith care.
Uses
Used in Organic Synthesis:
Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodois used as a reagent in organic synthesis for [application reason]. Its unique structure with bromo and iodo groups, along with the 1,1-dimethylethyl group, allows it to participate in a variety of chemical reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodois used as a building block for the development of new drugs. Its specific functional groups can be further modified or used as starting materials for the synthesis of bioactive compounds with potential therapeutic applications.
Used in Chemical Research:
Benzene, 1-bromo-3-(1,1-dimethylethyl)-5-iodois also used as a research tool in chemical laboratories. It can be employed to study the reactivity and selectivity of various chemical reactions, as well as to explore new synthetic methodologies and reaction mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 186772-43-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,7,7 and 2 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 186772-43:
(8*1)+(7*8)+(6*6)+(5*7)+(4*7)+(3*2)+(2*4)+(1*3)=180
180 % 10 = 0
So 186772-43-0 is a valid CAS Registry Number.
186772-43-0Relevant articles and documents
Design and Optimization of 3′-(Imidazo[1,2- a]pyrazin-3-yl)-[1,1′-biphenyl]-3-carboxamides as Selective DDR1 Inhibitors
Mo, Cheng,Zhang, Zhang,Li, Yupeng,Huang, Minhao,Zou, Jian,Luo, Jinfeng,Tu, Zheng-Chao,Xu, Yong,Ren, Xiaomei,Ding, Ke,Lu, Xiaoyun
, p. 379 - 384 (2020)
DDR1 is considered as a promising target for cancer therapy, and selective inhibitors against DDR1 over other kinases may be considered as promising therapeutic agents. Herein, we have identified a series of 3′-(imidazo[1,2-a]pyrazin-3-yl)-[1,1′-biphenyl]
Synthesis of butadiyne-bridged [4n] metacyclophanes having exo-annular t-butyl groups
Tobe, Yoshito,Utsumi, Naoto,Nagano, Atsushi,Sonoda, Motohiro,Naemura, Koichiro
, p. 8075 - 8083 (2007/10/03)
Butadiyne-bridged [44]- and [48]metacyclophanes having exo-annular t-butyl groups were prepared by intermolecular Eglinton coupling of the dimeric unit or by intramolecular ring closure of the linear tetramer. Comparison of the 1H and 13C NMR spectra of [44]metacyclophane with those of [48]cyclophane and diphenylbutadiyne revealed its prominent geometrical feature due to deformation of the triple bonds from linearity. The [44]Metacyclophane was converted into [08]thiophenometacyclophane in good yield by treatment with sodium sulfide.