18684-97-4

Basic information

• Product Name: (E)-1-(2-chlorovinyl)-4-chlorobenzene
• Synonyms: (E)-1-(2-chlorovinyl)-4-chlorobenzene
• CAS NO: 18684-97-4
• Molecular Weight: 173.042
• Mol File: 18684-97-4.mol
• Article Data: 22

Chemical Properties

• CAS DataBase Reference: (E)-1-(2-chlorovinyl)-4-chlorobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(2-chlorovinyl)-4-chlorobenzene(18684-97-4)
• EPA Substance Registry System: (E)-1-(2-chlorovinyl)-4-chlorobenzene(18684-97-4)

Safety Data

• Hazardous Substances Data: 18684-97-4(Hazardous Substances Data)

Upstream product

• 1073-67-2 4-vinylbenzyl chloride 
• 156-60-5 trans-1,2-dichloroethylene 
• 168006-99-3 (E)-1-chloro-4-(2-iodovinyl)benzene 
• 66482-29-9 1-[(E)-2-bromoethenyl]-4-chlorobenzene 
• 87-90-1 trichloroisocyanuric acid 
• 1615-02-7 3-(4-chlorophenyl)prop-2-enoic acid 
• 103721-98-8 (4R,5R)-4-Chloro-5-(4-chloro-phenyl)-[1,3]oxathiolane 3,3-dioxide 
• 91309-66-9 3-chloro-3-(p-chlorobenzyl)diazirine 
• 107-21-1 ethylene glycol 
• 88211-10-3 p-chlorobenzyl(chloro)carbene 
• 691-38-3 (Z)-4-methyl-2-pentene 
• 64-17-5 ethanol 
• 67-56-1 methanol 
• 104-88-1 4-chlorobenzaldehyde 

Downstream Products

• 824-90-8 1-phenylbut-1-ene 
• 886-65-7 1,4-diphenyl-1,3-butadiene 
• 1083-56-3 1,4-diphenylbutane 
• 104-51-8 1-butylbenzene 
• 3041-83-6 (E)-4-chloro-4'-methylstilbene 
• 1657-50-7 (E)-1-(4-chlorophenyl)-2-phenylethene 
• 27486-17-5 (E)-1-(4-chlorostyryl)-2-methylbenzene 

Relevant articles and documents

Continuous Flow Chlorination of Alkenyl Iodides Promoted by Copper Tubing

A simple continuous flow synthesis of alkenyl chlorides from the corresponding readily available alkenyl iodides in copper reactor tubing is described. A variety of alkenyl chlorides were obtained in good to excellent yields with full retention of the dou

Kinetically controlled E-selective catalytic olefin metathesis

A major shortcoming in olefin metathesis, a chemical process that is central to research in several branches of chemistry, is the lack of efficient methods that kinetically favor E isomers in the product distribution. Here we show that kinetically E-selective cross-metathesis reactions may be designed to generate thermodynamically disfavored alkenyl chlorides and fluorides in high yield and with exceptional stereoselectivity.With 1.0 to 5.0 mole % of a molybdenum-based catalyst, which may be delivered in the form of air- and moisture-stable paraffin pellets, reactions typically proceed to completion within 4 hours at ambient temperature. Many isomerically pure E-alkenyl chlorides, applicable to catalytic cross-coupling transformations and found in biologically active entities, thus become easily and directly accessible. Similarly, E-alkenyl fluorides can be synthesized from simpler compounds or more complex molecules.

A General Copper-Catalyzed Vinylic Halogen Exchange Reaction

An efficient and general system for the halogen exchange reaction in alkenyl halides has been developed. Upon reaction with catalytic amounts of copper iodide and trans-N,N′-dimethylcyclohexane-1,2-diamine in the presence of tetramethylammonium chloride or bromide, a wide range of easily accessible alkenyl iodides can be smoothly transformed to their far less available chlorinated and brominated derivatives in excellent yields and with full retention of the double bond geometry. This reaction also enables the chlorination of bromoalkenes and could be extended to the use of gem-dibromoalkenes.