187149-02-6

Basic information

• Product Name: N-(2-chlorothiazol-5-ylmethyl)-O-methyl-N'-nitroisourea
• CAS NO: 187149-02-6
• Molecular Weight: 250.666
• Mol File: 187149-02-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(2-chlorothiazol-5-ylmethyl)-O-methyl-N'-nitroisourea(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-chlorothiazol-5-ylmethyl)-O-methyl-N'-nitroisourea(187149-02-6)
• EPA Substance Registry System: N-(2-chlorothiazol-5-ylmethyl)-O-methyl-N'-nitroisourea(187149-02-6)

Safety Data

• Hazardous Substances Data: 187149-02-6(Hazardous Substances Data)

Upstream product

• 153471-67-1 2-chloro-5-(aminomethyl)thiazole hydrochloride 
• 57538-27-9 O-methyl-N-nitroisourea 

Downstream Products

• 210880-92-5 clothianidine 
• 205510-53-8 clothianidin 

Relevant articles and documents

METHOD FOR NITRATING ISOUREA

An object of the present invention is to industrially advantageously produce N-nitroisoureas or a salt thereof which is useful as a synthetic intermediate for pharmaceuticals and pesticides. The present invention relates to a process for producing a compound represented by the formula (2): wherein R1, R2 and R3 are as defined below, or a salt thereof, which comprises reacting a compound represented by the formula (1): wherein R1 represents an optionally substituted straight-chain or branched C1 to C6 alkyl group, R2 and R3 are the same or different and represent an optionally substituted straight-chain or branched C1 to C6 alkyl group, a cycloalkyl group or a substituted aryl group, or R2 and R3 simultaneously represent a hydrogen atom, or a salt thereof with a nitrating agent in the presence of sulfur trioxide.