187235-47-8 Usage
Description
(6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate is a complex organic molecule with a nitro group, a dihydro-imidazo ring, an oxazin ring, and a carbamate functional group attached to a phenyl ring with a trifluoromethoxy substituent. It has a stereocenter at the 6th position with the stereochemistry specified as (6S). (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate is likely to possess pharmacological or biological properties and is commonly used as a research tool in medicinal chemistry due to its intricate structure and the presence of a carbamate group, which is prevalent in pharmaceuticals and bioactive compounds. The nitro group in the molecule may also contribute to its reactivity or pharmacological activity.
Uses
Used in Pharmaceutical Industry:
(6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate is used as a potential pharmaceutical compound for its possible pharmacological properties. The presence of the carbamate group and the nitro group suggests that it may have applications in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate serves as a valuable research tool. Its complex structure allows scientists to study its interactions with various biological targets, potentially leading to the discovery of new therapeutic agents or a better understanding of molecular mechanisms involved in diseases.
Used in Chemical Synthesis:
(6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate may also be utilized in chemical synthesis processes, particularly for the creation of other complex organic molecules or as intermediates in the synthesis of pharmaceuticals. Its unique structure and functional groups make it a candidate for further modification and exploration in the synthesis of novel bioactive compounds.
Used in Drug Design:
(6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate can be employed in drug design, where its structure may be optimized to enhance its pharmacological activity, selectivity, and safety profile. (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)phenyl]carbamate's carbamate group and nitro group can be key features in the design of new drugs targeting specific diseases or conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 187235-47-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,2,3 and 5 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 187235-47:
(8*1)+(7*8)+(6*7)+(5*2)+(4*3)+(3*5)+(2*4)+(1*7)=158
158 % 10 = 8
So 187235-47-8 is a valid CAS Registry Number.
187235-47-8Relevant articles and documents
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl] oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Blaser, Adrian,Palmer, Brian D.,Sutherland, Hamish S.,Kmentova, Iveta,Franzblau, Scott G.,Wan, Baojie,Wang, Yuehong,Ma, Zhenkun,Thompson, Andrew M.,Denny, William A.
experimental part, p. 312 - 326 (2012/03/07)
Analogues of clinical tuberculosis drug (6S)-2-nitro-6-{[4- (trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824), in which the OCH2 linkage was replaced with amide, carbamate, and urea functionality, were investigate
