187235-52-5 Usage
Description
(6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)benzyl]carbamate is a complex chemical compound with a unique structure. It features a nitro group, a dihydro-imidazo ring system, an oxazin ring, and a carbamate functional group. The (6S) configuration denotes the stereochemistry of the compound. The presence of trifluoromethoxy and benzyl groups suggests potential pharmacological or biological activity. (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)benzyl]carbamate holds promise for various applications, particularly in drug discovery and development, as well as in medicinal chemistry research. Further experimental studies are required to explore its specific properties and potential uses.
Uses
Used in Drug Discovery and Development:
(6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)benzyl]carbamate is used as a lead compound for drug discovery and development due to its complex structure and potential pharmacological or biological activity. Its unique features, including the nitro group, dihydro-imidazo ring system, oxazin ring, and carbamate functional group, make it a promising candidate for further investigation and optimization in the development of new therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)benzyl]carbamate serves as a valuable research tool. Its intricate structure and the presence of functional groups such as trifluoromethoxy and benzyl make it an interesting subject for studying the relationship between chemical structure and biological activity. (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4-(trifluoromethoxy)benzyl]carbamate can be utilized to explore new mechanisms of action, target identification, and the development of novel therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 187235-52-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,7,2,3 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 187235-52:
(8*1)+(7*8)+(6*7)+(5*2)+(4*3)+(3*5)+(2*5)+(1*2)=155
155 % 10 = 5
So 187235-52-5 is a valid CAS Registry Number.
187235-52-5Relevant articles and documents
Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl] oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)
Blaser, Adrian,Palmer, Brian D.,Sutherland, Hamish S.,Kmentova, Iveta,Franzblau, Scott G.,Wan, Baojie,Wang, Yuehong,Ma, Zhenkun,Thompson, Andrew M.,Denny, William A.
supporting information; experimental part, p. 312 - 326 (2012/03/07)
Analogues of clinical tuberculosis drug (6S)-2-nitro-6-{[4- (trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824), in which the OCH2 linkage was replaced with amide, carbamate, and urea functionality, were investigate
