187336-26-1

Basic information

• Product Name: tert-Butyl-diphenyl-[(4E,8E,12E)-4,9,13-trimethyl-15-((R)-2,2,5,5-tetramethyl-[1,3]dioxolan-4-yl)-pentadeca-4,8,12-trienyloxy]-silane
• Synonyms: tert-Butyl-diphenyl-[(4E,8E,12E)-4,9,13-trimethyl-15-((R)-2,2,5,5-tetramethyl-[1,3]dioxolan-4-yl)-pentadeca-4,8,12-trienyloxy]-silane
• CAS NO: 187336-26-1
• Molecular Weight: 631.027
• Mol File: 187336-26-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-Butyl-diphenyl-[(4E,8E,12E)-4,9,13-trimethyl-15-((R)-2,2,5,5-tetramethyl-[1,3]dioxolan-4-yl)-pentadeca-4,8,12-trienyloxy]-silane(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl-diphenyl-[(4E,8E,12E)-4,9,13-trimethyl-15-((R)-2,2,5,5-tetramethyl-[1,3]dioxolan-4-yl)-pentadeca-4,8,12-trienyloxy]-silane(187336-26-1)
• EPA Substance Registry System: tert-Butyl-diphenyl-[(4E,8E,12E)-4,9,13-trimethyl-15-((R)-2,2,5,5-tetramethyl-[1,3]dioxolan-4-yl)-pentadeca-4,8,12-trienyloxy]-silane(187336-26-1)

Safety Data

• Hazardous Substances Data: 187336-26-1(Hazardous Substances Data)

Upstream product

• 187336-24-9 (2E,6E,4'R)-(2',2',5'-trimethyl-1',3'-oxolan-4'-yl)-3,7-dimethylnona-2,6-dien-1-ol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 130790-62-4 (R,2E,6E)-10,11-dihydroxy-3,7,11-trimethyldodeca-2,6-dienyl acetate 
• 130790-63-5 (2E,6E)-3,7-dimethyl-9-((R)-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)nona-2,6-dienyl acetate 
• 4128-17-0 (2E,6E)-farnesyl acetate 
• 187336-25-0 (10R)-10,11-isopropylidenedioxy-10,11-dihydrofarnesyl bromide 

Downstream Products

• 187336-28-3 Methanesulfonic acid (4E,8E,12E)-(R)-16-(tert-butyl-diphenyl-silanyloxy)-1-(1-hydroxy-1-methyl-ethyl)-4,8,13-trimethyl-hexadeca-4,8,12-trienyl ester 
• 187336-29-4 tert-Butyl-[(4E,8E,12E)-15-((S)-3,3-dimethyl-oxiranyl)-4,9,13-trimethyl-pentadeca-4,8,12-trienyloxy]-diphenyl-silane 
• 187397-59-7 (3S)-(6E,10E,14E,18Z)-2,3-Epoxy-2,6,10,15,23-pentamethyl-19-vinyl-6,10,14,18,22-tetracosapentaene 
• 187336-27-2 (6E,10E,14E)-(R)-18-(tert-Butyl-diphenyl-silanyloxy)-2,6,10,15-tetramethyl-octadeca-6,10,14-triene-2,3-diol 

Relevant articles and documents

Potency and inactivation rates of analogues of an irreversible inhibitor of vertebrate oxidosqualene cyclase

Truncated, 22(23)-dihydro, and fluorinated analogues of (3S)-29-methylidene-2,3-oxidosqualene (29-MOS) were prepared and inhibitory potencies and rates of inactivation of rat oxidosqualene cyclase were measured. Rapid mechanism-based enzyme inactivation was observed for both methylidene and difluoromethylidene analogues with complete pro-side chains, but not for truncated analogues.