187526-92-7

Basic information

• Product Name: (S)-tert-butyl 1-(1,3-dioxoisoindolin-2-yl)-3-phenylpropan-2-ylcarbamate
• CAS NO: 187526-92-7
• Molecular Weight: 380.444
• Mol File: 187526-92-7.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 1-(1,3-dioxoisoindolin-2-yl)-3-phenylpropan-2-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 1-(1,3-dioxoisoindolin-2-yl)-3-phenylpropan-2-ylcarbamate(187526-92-7)
• EPA Substance Registry System: (S)-tert-butyl 1-(1,3-dioxoisoindolin-2-yl)-3-phenylpropan-2-ylcarbamate(187526-92-7)

Safety Data

• Hazardous Substances Data: 187526-92-7(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 3182-95-4 L-Phenylalaninol 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 126301-19-7 (2S)-2-[(tert-butoxycarbonyl)amino]-3-phenylpropyl methanesulfonate 
• 1074-82-4 potassium phtalimide 
• 66605-57-0 (S)-N-tert-butoxycarbonyl-2-amino-3-phenylpropanol 
• 136918-14-4 phthalimide 

Downstream Products

• 187526-95-0 2-[(2S)-2-amino-3-phenylpropyl]-1H-isoindole-1,3(2H)-dione hydrochloride: 
• 146552-72-9 (S)-2-(t-butoxycarbonylamino)-3-phenylpropylamine 
• 359015-30-8 tert-Butyl-N-{(1S)-1-benzyl-2-[(4-nitrobenzoyl)amino]ethyl}carbamate 
• 169267-14-5 YG*CH₂G^u*CH₂F^u*L-Amid 

Relevant articles and documents

Chiral Cyclopropenimine-catalyzed Asymmetric Michael Addition of Bulky Glycine Imine to α,β-Unsaturated Isoxazoles

A highly efficient asymmetric Michael addition of bulky glycine imine to α,β-unsaturated isoxazoles has been achieved by using 5 mol% of chiral cyclopropenimine as a chiral organo-superbase catalyst under mild conditions. Michael adducts were obtained in excellent yields (up to 97%) and stereoselectivities (up to >99 : 1 dr and 98% ee). A significant solvent effect was found in these chiral organosuperbase catalyzed asymmetric Michael reactions. Gram-scale preparation of Michael adducts and their transformations are realized to provide corresponding products without loss of stereoselectivities. The configurations of Michael adduct was determined by single-crystal X-ray diffraction analysis.

Asymmetric Multicomponent Sulfa-Michael/Mannich Cascade Reaction: Synthetic Access to 1,2-Diamino-3-Organosulfur Compounds and 2-Nitro Allylic Amines

A novel catalytic asymmetric three-component intermolecular sulfa-Michael/Mannich cascade reaction has been developed using a chiral multifunctional catalyst. This reaction provides facile access to 1-amino-2-nitro-3-organosulfur compounds bearing three c

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