187672-13-5

Basic information

• Product Name: (E)-1-(3-methoxyphenyl)ethan-1-one oxime
• Synonyms: (E)-1-(3-methoxyphenyl)ethan-1-one oxime
• CAS NO: 187672-13-5
• Molecular Weight: 165.192
• Mol File: 187672-13-5.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: (E)-1-(3-methoxyphenyl)ethan-1-one oxime(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(3-methoxyphenyl)ethan-1-one oxime(187672-13-5)
• EPA Substance Registry System: (E)-1-(3-methoxyphenyl)ethan-1-one oxime(187672-13-5)

Safety Data

• Hazardous Substances Data: 187672-13-5(Hazardous Substances Data)

Upstream product

• 586-37-8 1-(3-Methoxyphenyl)ethanone 
• 50919-07-8 1-(3-methoxy-phenyl)-ethylamine 

Downstream Products

• 847834-51-9 6-hydroxymethyl-3-(3-methoxyphenyl)-5,6-dihydro-4H-1,2-oxazine 
• 50919-07-8 1-(3-methoxy-phenyl)-ethylamine 
• 50919-07-8 (S)-1-(3-methoxyphenyl)ethylamine 
• 88196-70-7 (R)-1-(3-methoxyphenyl)ethylamine 
• 1384454-55-0 (E)-1-(3-methoxyphenyl)ethanone O-benzyl oxime 
• 26870-34-8 2-(3’-methoxyphenyl)benzofuran 
• 1051939-28-6 1-(3-methoxyphenyl)pent-4-en-1-one oxime 
• 356758-04-8 5-(Furan-3-yl)-3-(3-methoxyphenyl)-isoxazole 
• 588-16-9 m-methoxyacetanilide 

Relevant articles and documents

One-pot two-step sequential transformation: Highly efficient construction of o-2,3,5,6-tetrafluorobenzonitrile substituted oximes ethers

A practical variety of o-2,3,5,6-tetrafluorobenzonitrile substituted oximes ethers bearing broad functional groups were synthesized in moderate to good yields. The key highlight of this disclosure involving a one-pot two-step tandem procedure in aqueous media: the in situ formation of aryl aldehydes or ketones oximes followed by the SNAr reaction with pentafluorobenzonitrile via the high selective CF bond cleavage.

Copper-catalyzed synthesis of oxime ethers from iminoxy radical (C[dbnd]N–O[rad]) and maleimides via radical addition

An efficient Cu(II)-catalyzed radical addition of maleimides has been achieved. The identified copper catalyst enables the formation of oxime radicals (N–O[rad]) by cleaving the O–H bond in ketoximes, followed by the radical addition to N-substituted male

Dichloroimidazolidinedione-Activated Beckmann Rearrangement of Ketoximes for Accessing Amides and Lactams

A novel protocol for the activation of the Beckmann rearrangement utilizing the readily available and economical geminal dichloroimidazolidinediones (DCIDs) on a substoichiometric scale (10 mol %) has been developed. A unique self-propagating mechanism for the substoichiometric dichloroimidazolidinedione-activated transformation was proposed and validated. The substrate scope of the developed protocol has been demonstrated by 23 examples with good to excellent yields (mostly 90-98%) in a short time (mostly 10-30 min), including a substrate for synthesizing the monomer of nylon-12 and a complicated steroidal substrate on a preparative scale. This research not only unveils for the first time the synthetic potential of substoichiometric amounts of dichloroimidazolidinediones in promoting chemical transformation but also offers yet another important illustration of the self-propagating cycle in the context of the Beckmann rearrangement activated by a structurally novel organic promoter.