187722-18-5

Basic information

• Product Name: 3-(METHYLTHIO)-1-(TOSYLOXY)PROPANE
• Synonyms: 3-(METHYLTHIO)-1-(TOSYLOXY)PROPANE;Toluene-4-sulfonic acid 3-methylsulfanyl-propyl ester;3-(Methylthio)propyl 4-Methylbenzenesulfonate;3-(Methylthio)propyl tosylate;3-(METHYLTHIO)-1-(TOSYLOXY)PROPANE-2
• CAS NO: 187722-18-5
• Molecular Formula: C₁₁H₁₆O₃S₂
• Molecular Weight: 260.37294
• Product Categories: Aromatics Compounds;Aromatics;Sulfur & Selenium Compounds
• Mol File: 187722-18-5.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 403.2±28.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• Solubility: Chloroform, Dichloromethane, Ethyl Acetate
• CAS DataBase Reference: 3-(METHYLTHIO)-1-(TOSYLOXY)PROPANE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(METHYLTHIO)-1-(TOSYLOXY)PROPANE(187722-18-5)
• EPA Substance Registry System: 3-(METHYLTHIO)-1-(TOSYLOXY)PROPANE(187722-18-5)

Safety Data

• Hazardous Substances Data: 187722-18-5(Hazardous Substances Data)

Usage

Description

3-(METHYLTHIO)-1-(TOSYLOXY)PROPANE is a white solid chemical compound that serves as an important intermediate in the synthesis of pharmaceutical compounds.

Uses

Used in Pharmaceutical Industry:
3-(METHYLTHIO)-1-(TOSYLOXY)PROPANE is used as a key intermediate in the synthesis of thiophene sulfonamides, which are carbonic anhydrase inhibitors. These inhibitors play a crucial role in the development of drugs for the treatment of various diseases, including glaucoma, epilepsy, and altitude sickness, by modulating the activity of the enzyme carbonic anhydrase.

Upstream product

• 505-10-2 3-(methylthio)-1-propanol 
• 98-59-9 p-toluenesulfonyl chloride 
• 74-93-1 methylthiol 
• 4873-09-0 allyl tosylate 

Downstream Products

• 263400-88-0 3-(methylsulfonyl)propyl 4-methylbenzenesulfonate 
• 944954-12-5 benzyl (3R,4R,5S)-3-[4-(3-methoxypropyl)-3,4-dihydro-2H-benzo[1,4]oxazin-6-ylmethoxy]-4-[4-(3-methylsulfanylpropoxy)phenyl]-5-triisopropylsilanyloxypiperidine-1-carboxylate 
• 59121-24-3 4-(methylthio)butyronitrile 
• 190385-32-1 methyl(5-phenylpent-4-yn-1-yl)sulfane 

Relevant articles and documents

Synthesis of β-dimethylsulfonium- and β-methylthio-substituted vinyl triflates by reaction of acetylenes with dimethyl sulfide ditriflate

A one-pot synthesis of β-dimethylsulfonium-substituted vinyl triflates by the reaction of dimethyl sulfide ditriflate with acetylenes is described. β-Dimethylsulfonium-substituted vinyl triflates were found to exhibit unusual reactivity towards nucleophil

SYNTHESIS OF 3-({5-CHLORO-1-[3-(METHYLSULFONYL)PROPYL]-1H-INDOL-2 YL} METHYL)-1-(2,2,2-TRIFLUOROETHYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE

The present invention relates to a chemical synthesis route for preparing the RSV inhibiting compound 3-({5-chloro-1-[3-(methylsulfonyl)propyl]-1H-indol-2-yl}methyl)-1-(2,2,2-trifluoroethyl)-10 1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one, and to new compounds used as intermediate compounds in the multistep process.

4-diphenylcarboxylic acid compound and preparing method and application thereof

The invention relates to a 4-diphenylcarboxylic acid compound and a preparing method and application thereof, and belongs to the field of medicines. The 4-diphenylcarboxylic acid compound is shown inthe formula I. The 4-diphenylcarboxylic acid compound ex