18799-86-5Relevant articles and documents
Photochemical Synthesis of Phenyl-2-thienyl Derivatives
Antonioletti, Roberto,Auria, Maurizio D',Onofrio, Franco D',Piancatelli, Giovanni,Scettri, Arrigo
, p. 1755 - 1758 (2007/10/02)
The irradiation (in benzene solution) of 5-bromo- and 5-iodo-thiophene-2-carbaldehyde or the corresponding methyl ketones furnishes the corresponding 5-phenyl derivatives.The same reactivity for other halogenothiophenes is reported: 3,5-dibromothiophene-2-carbaldehyde furnishes the 3-bromo-5-phenyl-2-thienyl derivative while the corresponding di-iodo compound yields 3,5-diphenylthiophene-2-carbaldehyde.In contrast, 5-acetyl-2,3-di-iodothiophene furnishes only the photosubstitution pruduct at C-5.Generally the iodine-containing compounds are more reactive and more stable under the reaction conditions than ones bearing bromine, in agreement with previous reports on the corresponding furan photochemistry.
