187993-58-4

Basic information

• Product Name: (2R)-1-benzyloxycarbonyl-2-(4,5-diphenyloxazol-2-yl)pyrrolidine
• Synonyms: (2R)-1-benzyloxycarbonyl-2-(4,5-diphenyloxazol-2-yl)pyrrolidine
• CAS NO: 187993-58-4
• Molecular Weight: 424.499
• Mol File: 187993-58-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R)-1-benzyloxycarbonyl-2-(4,5-diphenyloxazol-2-yl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-1-benzyloxycarbonyl-2-(4,5-diphenyloxazol-2-yl)pyrrolidine(187993-58-4)
• EPA Substance Registry System: (2R)-1-benzyloxycarbonyl-2-(4,5-diphenyloxazol-2-yl)pyrrolidine(187993-58-4)

Safety Data

• Hazardous Substances Data: 187993-58-4(Hazardous Substances Data)

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 6404-31-5 Z-D-proline 

Downstream Products

• 187992-65-0 (2R)-2-(4,5-diphenyloxazol-2-yl)-1-(3-ethoxycarbonylmethoxybenzyl)pyrrolidine 
• 187993-59-5 (2R)-2-(4,5-diphenyloxazol-2-yl)pyrrolidine 

Relevant articles and documents

Replacing the cyclohexene-linker of FR181157 leading to novel IP receptor agonists: Orally active prostacyclin mimetics. Part 6

The synthesis and biological activity of novel derivatives of our previously reported IP receptor agonist FR181157 is described. SAR studies to replace the cyclohexene-linker of FR181157 led to the discovery of compound 1i (FR207845) as a potent non-prost