188057-24-1

Basic information

• Product Name: 6-CHLORO-3-PYRIDINYL ACETATE
• Synonyms: 6-CHLORO-3-PYRIDINYL ACETATE;5-ACETYLOXY-2-CHLOROPYRIDINE;Acetic acid 6-chloro-pyridin-3-yl ester;6-Chloropyridin-3-yl acetate
• CAS NO: 188057-24-1
• Molecular Formula: C₇H₆ClNO₂
• Molecular Weight: 171.58
• Mol File: 188057-24-1.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 260.4°C at 760 mmHg
• Flash Point: 111.3°C
• Appearance: /
• Density: 1.297g/cm³
• Vapor Pressure: 0.0123mmHg at 25°C
• Refractive Index: 1.525
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-CHLORO-3-PYRIDINYL ACETATE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CHLORO-3-PYRIDINYL ACETATE(188057-24-1)
• EPA Substance Registry System: 6-CHLORO-3-PYRIDINYL ACETATE(188057-24-1)

Safety Data

• Hazardous Substances Data: 188057-24-1(Hazardous Substances Data)

Usage

General Description

6-Chloro-3-pyridinyl acetate is a chemical compound with the molecular formula C7H6ClNO2. It is a white crystalline solid and is commonly used as an intermediate in the synthesis of pharmaceuticals and agricultural chemicals. 6-CHLORO-3-PYRIDINYL ACETATE is a derivative of pyridine and contains a chlorine atom and an acetate group. It is known for its mild, fruity odor and is primarily used in the production of pyridine derivatives and agricultural pesticides. It is considered to be a hazardous chemical and should be handled with caution, following proper safety protocols and guidelines for storage and disposal.

InChI:InChI=1/C7H6ClNO2/c1-5(10)11-6-2-3-7(8)9-4-6/h2-4H,1H3

Upstream product

• 64-19-7 acetic acid 
• 5350-93-6 6-Chloro-pyridin-3-ylamine 
• 110-46-3 isopentyl nitrite 
• 108-24-7 acetic anhydride 

Downstream Products

• 198283-74-8 (R)-5-(2-azetidinylmethoxy)-2-chloropyridine p-toluenesulfonic acid salt 
• 527750-28-3 (E)-4-(6-Chloro-2-iodo-pyridin-3-yloxy)-4-cyclohexyl-but-2-enoic acid methyl ester 
• 527750-29-4 (E)-4-(6-Chloro-2-iodo-pyridin-3-yloxy)-4-phenyl-but-2-enoic acid methyl ester 
• 188057-26-3 6-chloro-2-iodopyridine-3-ol 
• 41288-96-4 6-chloropyridine-3-ol 

Relevant articles and documents

AMIDOPYRAZOLE DERIVATIVE

A platelet coagulation inhibitor which inhibits neither COX-1 nor COX-2 is provided. The inhibitor is a compound represented by general formula (I): wherein Ar1 and Ar2 independently represent a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents, or a phenyl group optionally substituted with 1 to 3 substituents; R1 represents a lower acyl group, carboxyl group, a lower alkoxycarbonyl group, a lower alkoxy group, a lower alkyl group optionally substituted with 1 or 2 substituents, a carbamoyl group optionally substituted with 1 or 2 substituents, an oxamoyl group optionally substituted with 1 or 2 substituents, an amino group optionally substituted with 1 or 2 substituents, a 4- to 7-membered alicyclic heterocyclic group optionally substituted with 1 or 2 substituents, a phenyl group optionally substituted with 1 to 3 substituents, or a 5- or 6-membered aromatic heterocyclic group optionally substituted with 1 to 3 substituents; and R2 represents hydrogen atom, a halogeno group, or the like.

5-HT1F agonists

The present invention relates to substituted furo[3,2-b]pyridine compounds of formula I: or a pharmaceutical acid addition salt thereof; where; R is E—D is C═CH or CH—CH2; R1is hydrogen or C1-C4alkyl; R2is hydrogen, halo, hydroxy, —NR3R4, —SR3, —C(O)R3, —C(O)MR3R4, —NR3SO2R5, —NHC(Q)NR3R4, —NHC(O)OR3, or —NR3C(O)R5; R3, R4, and R5are independently hydrogen, C1-C4alkyl, C2-C6alkenyl, C2-C6alkynyl, or —(CH2)naryl; or R3and R4combine, together with the nitrogen to which they are attached, form a pyrrolidine, piperidine, piperazine, 4-substituted piperazine, morpholine, or thiomorpholine ring; n is 0, 1, 2, 3, 4, 5, or 6; and Q is O or S. The present invention further relates to pharmaceutical. formulations containing compounds formula I and to the use of compounds of formula I for activating 5-HT1Freceptors, inhibiting neuronal protein extravasation, and treating and/or preventing migraine in a mammal.

3-PYRIDYLOXYMETHYL HETEROCYCLIC ETHER COMPOUNDS USEFUL IN CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION

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