18807-73-3 Usage
Description
BENZYL N-(4-AMINOBUTYL)CARBAMATE HYDROCHLORIDE, also known as N-Carbobenzoxy-1,4-diaminobutane HCl, is a white crystalline powder with significant applications in the pharmaceutical industry. It is a synthetic compound that serves as an essential intermediate in the development of various therapeutic agents.
Uses
Used in Pharmaceutical Industry:
BENZYL N-(4-AMINOBUTYL)CARBAMATE HYDROCHLORIDE is used as a synthetic intermediate for the development of pyrazolyl glucopyranoside and galactopyranoside derivative inhibitors. These inhibitors target human sodium-glucose cotransporter 1 (SGLT1) and are crucial in the prevention and treatment of diseases related to hyperglycemia or galactosemia. The compound plays a vital role in creating potential therapeutics that can help manage and treat these conditions more effectively.
Check Digit Verification of cas no
The CAS Registry Mumber 18807-73-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,8,0 and 7 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 18807-73:
(7*1)+(6*8)+(5*8)+(4*0)+(3*7)+(2*7)+(1*3)=133
133 % 10 = 3
So 18807-73-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H18N2O2/c13-8-4-5-9-14-12(15)16-10-11-6-2-1-3-7-11/h1-3,6-7H,4-5,8-10,13H2,(H,14,15)
18807-73-3Relevant articles and documents
Solution-Phase Synthesis of Backbone-Constrained Cationic Peptoid Hexamers with Antibacterial and Anti-Biofilm Activities
Charbonnel, Nicolas,Faure, Sophie,Forestier, Christiane,Roy, Olivier,Shyam, Radhe,Taillefumier, Claude
supporting information, p. 5813 - 5822 (2021/11/17)
Abstract: Submonomer synthesis in solution and block-coupling protocols were combined to prepare amphiphilic peptoid hexamers. The amphipathic character arises from the use of hydrophobic aliphatic tert-butyl side-chains imposing the cis-amide backbone co
An efficient and practical method for the synthesis of mono-N-protected α,ω-diaminoalkanes
Lee, Jae Wook,Jun, Sung Im,Kim, Kimoon
, p. 2709 - 2711 (2007/10/03)
The large-scale synthesis of mono-N-protected (Cbz, Boc, Ts, and Ns) α,ω-diaminoalkanes (the number of carbon atoms=3, 4, 5 and 6) are accomplished in 81-94% yield by the protection of amine and subsequent reduction of an azido group from α,ω-azido alkyl amines. α,ω-Azido alkyl amines are prepared efficiently by the partial reduction of α,ω-diazidoalkanes which are obtained from the corresponding dibromoalkanes.