188120-54-9

Basic information

• Product Name: (3S,4R,5R)-3,4-Dimethyl-5-trityloxymethyl-dihydro-furan-2-one
• CAS NO: 188120-54-9
• Molecular Weight: 386.491
• Mol File: 188120-54-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,4R,5R)-3,4-Dimethyl-5-trityloxymethyl-dihydro-furan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R,5R)-3,4-Dimethyl-5-trityloxymethyl-dihydro-furan-2-one(188120-54-9)
• EPA Substance Registry System: (3S,4R,5R)-3,4-Dimethyl-5-trityloxymethyl-dihydro-furan-2-one(188120-54-9)

Safety Data

• Hazardous Substances Data: 188120-54-9(Hazardous Substances Data)

Upstream product

• 101758-68-3 (R)-(+)-5-triphenylmethyloxymethyl-2 (5H)-furanone 
• 76-83-5 trityl chloride 
• 112837-17-9 (R)-(+)-5-(hydroxymethyl)furan-2(5H)-one 

Downstream Products

• 1026246-65-0 (2R,3R,4S)-4-(tert-Butyl-dimethyl-silanyloxy)-2,3-dimethyl-2-(3-oxo-2-trimethylsilanyl-butyl)-cyclohexanone 

Relevant articles and documents

Total synthesis of progesterone receptor ligands, (-)-PF1092A, B and C

Microbial metabolites (-)-PF1092A, B and C belonging to an eremophilane sesquiterpene group are synthesized from (R)-5-hydroxymethyl-2(5H)-furanone through the SnCl4 promoted cyclization of an α-keto methyl sulfone and dimethyl acetal followed by a Stork annulation which gives the octalone core.