188174-63-2 Usage
Description
Arachidonoyl Coenzyme A (C20:4) Lithium Salt, also known as Arachidonoyl CoA, is a vital molecule in cellular metabolism, particularly in the context of lipid metabolism. It is a derivative of coenzyme A and arachidonic acid, featuring a long-chain fatty acid structure. Arachidonoyl CoA plays a crucial role in various biochemical pathways and serves as a substrate for multiple enzymes, making it an essential component in the regulation of cellular processes.
Uses
Used in Biochemical Research:
Arachidonoyl CoA is used as a substrate for the long-chain N-acylation of glycines by enzymes such as glycine N-acyltransferase-like 2 (GLYATL2) and acyltransferases like lysophosphatidic acid acyltransferase (CGI-58/ABHD5). This application is vital for studying the mechanisms of lipid metabolism and the role of specific enzymes in these processes.
Used in Membrane Permeability Studies:
Arachidonoyl CoA is used as a charged membrane-impermeant analog of arachidonic acid (AA). This property makes it a valuable tool for investigating the transport of lipids across cellular membranes and understanding the factors that influence membrane permeability.
Used in Synthesis of Arachidonoyl Amino Acids:
Arachidonoyl CoA is used in the synthesis of arachidonoyl amino acids by cytochrome c. This application is essential for exploring the chemical reactions and pathways involved in the production of bioactive molecules derived from arachidonic acid, which have potential implications in various physiological and pathological conditions.
Biochem/physiol Actions
Arachidonoyl CoA is used as a charged membrane-impermeable analog of arachidonic acid (AA). It is used as a substrate for the long-chain N-acylation of glycines by enzymes such as glycine N-acyltransferase-like 2 (GLYATL2) in the presence of cytochrome c.
Check Digit Verification of cas no
The CAS Registry Mumber 188174-63-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,1,7 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 188174-63:
(8*1)+(7*8)+(6*8)+(5*1)+(4*7)+(3*4)+(2*6)+(1*3)=172
172 % 10 = 2
So 188174-63-2 is a valid CAS Registry Number.
InChI:InChI=1/C41H66N7O17P3S.Li/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-32(50)69-25-24-43-31(49)22-23-44-39(53)36(52)41(2,3)27-62-68(59,60)65-67(57,58)61-26-30-35(64-66(54,55)56)34(51)40(63-30)48-29-47-33-37(42)45-28-46-38(33)48;/h8-9,11-12,14-15,17-18,28-30,34-36,40,51-52H,4-7,10,13,16,19-27H2,1-3H3,(H,43,49)(H,44,53)(H,57,58)(H,59,60)(H2,42,45,46)(H2,54,55,56);/q;+1/p-1/b9-8+,12-11+,15-14+,18-17+;/t30-,34-,35-,36+,40-;/m1./s1
