188345-15-5

Basic information

• Product Name: 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1-(4-fluoro-phenyl)butane-1,4-dione
• Synonyms: 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1-(4-fluoro-phenyl)butane-1,4-dione
• CAS NO: 188345-15-5
• Molecular Weight: 474.532
• Mol File: 188345-15-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1-(4-fluoro-phenyl)butane-1,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1-(4-fluoro-phenyl)butane-1,4-dione(188345-15-5)
• EPA Substance Registry System: 4-(1-benzyloxycarbonylpiperidin-4-yl)-2-(pyridin-4-yl)-1-(4-fluoro-phenyl)butane-1,4-dione(188345-15-5)

Safety Data

• Hazardous Substances Data: 188345-15-5(Hazardous Substances Data)

Upstream product

• 160809-34-7 4-acetyl-piperidine-1-carboxylic acid benzyl ester 
• 6576-05-2 1-(4-fluorophenyl)-2-(4-pyridyl)ethanone 
• 816464-47-8 benzyl 4-(2-bromoacetyl)piperidine-1-carboxylate 
• 501-53-1 benzyl chloroformate 
• 10314-99-5 benzyl 4-(chlorocarbonyl)piperidine-1-carboxylate 
• 10314-98-4 1-benzyloxycarbonylpiperidine-4-carboxylic acid 
• 85475-10-1 4-(2-chloroacetyl)piperidine-1-carboxylic acid benzyl ester 
• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 108-89-4 picoline 

Downstream Products

• 1426406-57-6 N-(2-(4-(5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyrrol-2-yl)piperidin-1-yl)ethyl)-6-(6-(5-((3aS,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)hexanamido)hexanamide 
• 1426406-59-8 N-(2-(2-(2-(2-(3-(2-(4-(5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-pyrrol-2-yl)piperidin-1-yl)ethylamino)-3-oxopropoxy)ethoxy)ethoxy)ethoxy)ethyl)-5-((3aS,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide 
• 339988-84-0 2-(4-fluorophenyl)-5-(N-ethylpiperidin-4-yl)-3-(pyridin-4-yl)pyrrole 
• 188343-78-4 2-(4-fluorophenyl)-5-(piperidin-4-yl)-3-(pyridin-4-yl)-pyrrole 

Relevant articles and documents

THERAPEUTIC METHODS AND COMPOUNDS

The invention provides a compound of formula I: (I) or a pharmaceutically acceptable salt thereof, wherein R1-R5 Y have any of the values described in the specification, as well as compositions comprising a compound of formula I. The compounds are useful to treat malaria.

Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents

Several analogs of 2,3-diaryl pyrroles were synthesized and evaluated as inhibitors of Eimeria tenella cGMP-dependent protein kinase and in in vivo anticoccidial assays. A 4-fluorophenyl group enhances both in vitro and in vivo activities. The most potent

Aliphatic amine substituted piperidyl diaryl pyrrole derivatives as antiprotozoal agents

Trisubstituted pyrroles are antiprotozoal agents useful in the treatment and prevention of protozoal diseases in human and animals, including the control of coccidiosis in poultry.