188399-46-4 Usage
Description
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]is a complex organic compound with a unique molecular structure. It is characterized by a 6H-Purin-6-one core, which is a heterocyclic aromatic organic compound, and a 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]side chain. 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]exhibits a white solid form and is known for its antiviral properties.
Uses
Used in Pharmaceutical Industry:
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]is used as an enantiomeric impurity of the antiviral drug Entecavir (E558900). It plays a crucial role in the development and manufacturing process of Entecavir, ensuring the purity and efficacy of the final drug product. 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-'s presence in the pharmaceutical industry is essential for maintaining the quality and safety of antiviral medications.
Used in Chemical Research:
6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]is also used in chemical research for its unique molecular structure and properties. Researchers can study its chemical behavior, interactions with other compounds, and potential applications in various fields. 6H-Purin-6-one, 2-amino-1,9-dihydro-9-[(1R,3S,4R)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]can contribute to the advancement of knowledge in organic chemistry and the development of new pharmaceuticals and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 188399-46-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,8,3,9 and 9 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 188399-46:
(8*1)+(7*8)+(6*8)+(5*3)+(4*9)+(3*9)+(2*4)+(1*6)=204
204 % 10 = 4
So 188399-46-4 is a valid CAS Registry Number.
188399-46-4Relevant articles and documents
Process for preparing entecavir and intermediates thereof
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, (2013/06/06)
It comprises the preparation of entecavir of formula (I), or a pharmaceutically acceptable salt thereof, or a hydrate thereof by submitting a compound of formula (III) where X is an halogen selected from Cl, Br, and I, first to a hydrolysis reaction using formic acid and then to a deprotection reaction, and isolating the entecavir either as free base or as a pharmaceutically acceptable salt. It also comprises intermediates which intervene in this preparation process.