188549-20-4

Basic information

• Product Name: 2-cyclopropylidene-2-phenyl-1-phenoxy ethane
• CAS NO: 188549-20-4
• Molecular Weight: 236.313
• Mol File: 188549-20-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-cyclopropylidene-2-phenyl-1-phenoxy ethane(CAS DataBase Reference)
• NIST Chemistry Reference: 2-cyclopropylidene-2-phenyl-1-phenoxy ethane(188549-20-4)
• EPA Substance Registry System: 2-cyclopropylidene-2-phenyl-1-phenoxy ethane(188549-20-4)

Safety Data

• Hazardous Substances Data: 188549-20-4(Hazardous Substances Data)

Upstream product

• 721-04-0 2-phenoxy-1-phenylethanone 
• 3607-17-8 3-bromopropyltriphenylphosphonium bromide 
• 14633-95-5 triphenylphosphonium cyclopropylide 

Relevant articles and documents

Palladium (0) catalyzed nucleophilic substitution on 2-cyclopropylidene-phenoxy ethanes

2-cyclopropylidene-phenoxy ethanes 5, 2-substituted with alkyl, aryl or heterocyclic groups are readily obtained in high yields by the Wittig reaction of the easily accessible α-phenoxy etanones 4 with (3-bromo propyl) triphenylphosphonium bromide. They react with complete regioselectivity in palladium (0) catalyzed nucleophilic substitutions with a series of soft carbon nucleophiles giving an easy entry to 5,6-methanoamino acids.