188576-13-8

Basic information

• Product Name: Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester
• CAS NO: 188576-13-8
• Molecular Formula: C15H21NO5
• Molecular Weight: 295.335
• Mol File: 188576-13-8.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(188576-13-8)
• EPA Substance Registry System: Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-, methyl ester(188576-13-8)

Safety Data

• Hazardous Substances Data: 188576-13-8(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 1186627-71-3 methyl N-Boc-3-tert-butyltyrosinate 
• 1538-75-6 2,2-dimethylpropanoic anhydride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 556-02-5 ?Tyr 
• 186581-53-3 diazomethane 
• 142847-18-5 N-(tert-butoxycarbonyl)tyrosine 
• 1080-06-4 tyrosine methyl ester 
• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 3417-91-2 tyrosine methyl ester hydrochloride 

Downstream Products

• 914639-60-4 methyl 2-[(tert-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy) phenyl]propanoate 

Relevant articles and documents

Nickel-catalyzed deallylation of aryl allyl ethers with hydrosilanes

An efficient and mild catalytic deallylation method of aryl allyl ethers is developed, with commercially available Ni(COD)2 as catalyst precursor, simple substituted bipyridine as ligand and air-stable hydrosilanes. The process is compatible with a variety of functional groups and the desired phenol products can be obtained with excellent yields and selectivity. Besides, by detection or isolation of key intermediates, mechanism studies confirm that the deallylation undergoes η3-allylnickel intermediate pathway.

Photoinduced Vitamin B12-Catalysis for Deprotection of (Allyloxy)arenes

Vitamin B12 is a natural cobalt complex that, while reduced to the "supernucleophilic" Co(I) form, can easily react with electrophiles via an SN2 mechanism. It is also shown to react via an SN2′ mechanism with allylic compounds allowing for photochemical deprotection of (allyloxy)arenes. A sustainable alternative to commonly used noble metal-catalyzed deprotection reactions is presented.

A PRODUCING METHOD OF D-FORM OR L-FORM AMINO ACID DERIVATIVES HAVING A THIOL GROUP

This invention provides a producing method of an optical active D-form and/or L-form amino acid having a thiol group on its side chain by a simple method with good yield. This invention provides a producing method of an amino acid derivative having a thiol group on its side chain, and an intermediate thereof, wherein the producing method is characterized by producing an intermediate composition comprising a D-form and L-form of amino acid derivate having a thiol group at β -position, reacting D- or L-amino acid selective hydrolytic enzyme, and isolating the hydrolyzed D- or L-amino acid derivative.