188616-36-6

Basic information

• Product Name: Cyclohexanecarboxylic acid, 1-(2-butynyl)-2-oxo-, ethyl ester
• CAS NO: 188616-36-6
• Molecular Formula: C13H18O3
• Molecular Weight: 222.284
• Mol File: 188616-36-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 1-(2-butynyl)-2-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 1-(2-butynyl)-2-oxo-, ethyl ester(188616-36-6)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 1-(2-butynyl)-2-oxo-, ethyl ester(188616-36-6)

Safety Data

• Hazardous Substances Data: 188616-36-6(Hazardous Substances Data)

Upstream product

• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 61493-85-4 but-2-yn-1-yl methanesulfonate 
• 3355-28-0 1-Bromo-2-butyne 

Downstream Products

• 1187777-44-1 2-(tert-butyl-dimethyl-silanyloxy)-1-but-2-ynylcyclohex-2-enecarboxylic acid ethyl ester 
• 54166-48-2 2-(but-2-yn-1-yl)cyclohexan-1-one 
• 1330779-70-8 6-(buta-2-ynyl)-1-trimethylsiloxycyclohex-1-ene 

Relevant articles and documents

Nickel-Catalyzed α-1,3-Dienylation of 1,3-Dicarbonyl Compounds with Propargylic Carbonates

Herein reported is a nickel-catalyzed α-1,3-dienylation reaction of 1,3-dicarbonyl compounds with substituted propargylic (e.g., but-2-ynyl) carbonates. The propargyl unit changes into a 1,3-dienyl unit, which is incorporated at the α-position of the 1,3-dicarbonyl compounds.

Gold-catalyzed synthesis of carbon-bridged medium-sized rings

Bicyclo[m.n.1]alkenone frameworks possessing quaternary carbon centers adjacent to a bridged ketone are frequently found in bioactive natural products. Although several methods have been developed to construct such frameworks, most of them are specific to a particular scaffold. Herein, we report a mild and highly efficient method to generate carbon-bridged frameworks of various sizes using phosphlno gold(I) catalysts.