188617-17-6

Basic information

• Product Name: 12-Tridecenoic acid, 1-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-3-butenyl ester, (E)-
• CAS NO: 188617-17-6
• Molecular Formula: C24H37NO2S
• Molecular Weight: 403.629
• Mol File: 188617-17-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 12-Tridecenoic acid, 1-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-3-butenyl ester, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 12-Tridecenoic acid, 1-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-3-butenyl ester, (E)-(188617-17-6)
• EPA Substance Registry System: 12-Tridecenoic acid, 1-[1-methyl-2-(2-methyl-4-thiazolyl)ethenyl]-3-butenyl ester, (E)-(188617-17-6)

Safety Data

• Hazardous Substances Data: 188617-17-6(Hazardous Substances Data)

Upstream product

• 6436-59-5 ethyl 2-methylthiazole-4-carboxylate 
• 6006-06-0 12-tridecenoic acid 
• 188617-13-2 2-methyl-4-([1E]-2'-methylhexa-1',5'-dien-3'-ol)thiazole 

Relevant articles and documents

Towards the synthesis of epothilone A: Enantioselective preparation of the thiazole side-chain and macrocyclic ring closure

A synthetic approach to a new class of microtubule-stabilizing natural products is described which employs a macrocyclic olefination strategy to cyclize the 16-membered lactone ring. The C13-C19 thiazole subunit of epothilone A and B is prepared in high enantioselectivity using a catalytic asymmetric allylation reaction.