188624-22-8

Basic information

• Product Name: Propanedioic acid, (acetylamino)[(3-fluoro-4-nitrophenyl)methyl]-, diethyl ester
• CAS NO: 188624-22-8
• Molecular Formula: C16H19FN2O7
• Molecular Weight: 370.334
• Mol File: 188624-22-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Propanedioic acid, (acetylamino)[(3-fluoro-4-nitrophenyl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanedioic acid, (acetylamino)[(3-fluoro-4-nitrophenyl)methyl]-, diethyl ester(188624-22-8)
• EPA Substance Registry System: Propanedioic acid, (acetylamino)[(3-fluoro-4-nitrophenyl)methyl]-, diethyl ester(188624-22-8)

Safety Data

• Hazardous Substances Data: 188624-22-8(Hazardous Substances Data)

Upstream product

• 446-34-4 2-fluoro-4-methyl-1-nitrobenzene 
• 131858-37-2 4-(bromomethyl)-2-fluoro-1-nitrobenzene 
• 1068-90-2 2-acetylaminomalonic acid diethyl ester 

Downstream Products

• 370-54-7 (R,S)-3-fluoro-4-nitrophenylalanine hydrochloride 
• 188624-25-1 3-(3-Fluoro-4-nitro-phenyl)-2-(2,2,2-trifluoro-acetylamino)-propionic acid methyl ester 
• 188624-29-5 (S)-N-trifluoroacetyl-3-fluoro-4-nitrophenylalanine 
• 160247-85-8 (S)-3-fluoro-4-nitrophenylalanine methyl ester 

Relevant articles and documents

Synthesis and Evaluation of Macrocyclic Peptide Aldehydes as Potent and Selective Inhibitors of the 20S Proteasome

This research explores the first design and synthesis of macrocyclic peptide aldehydes as potent inhibitors of the 20S proteasome. Two novel macrocyclic peptide aldehydes based on the ring-size of the macrocyclic natural product TMC-95 were prepared and e