18866-87-0 Usage
Description
(3R,5S,7R,8R,9S,10S,12S,13R,14S)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is a complex organic compound with a long, cyclical structure. It is a type of sterol, specifically a type of phytosterol, which is a plant-based steroid alcohol. This chemical has several hydroxyl (OH) groups attached to its carbon atoms, making it a polyhydroxy compound. It is classified as a terpene, a large and diverse class of organic compounds that are produced by a variety of plants and some insects. This particular chemical has a significant number of carbon atoms in its structure, giving it multiple sites for potential interactions and reactions in biological systems.
Uses
Used in Pharmaceutical Industry:
(3R,5S,7R,8R,9S,10S,12S,13R,14S)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is used as a pharmaceutical compound for its potential therapeutic properties. Its complex structure and multiple hydroxyl groups allow for interactions with various biological targets, making it a promising candidate for the development of new drugs.
Used in Cosmetic Industry:
In the cosmetic industry, (3R,5S,7R,8R,9S,10S,12S,13R,14S)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is used as an active ingredient for its potential skin benefits. Its ability to interact with biological systems may contribute to improved skin health and appearance.
Used in Agrochemical Industry:
(3R,5S,7R,8R,9S,10S,12S,13R,14S)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol is used in the agrochemical industry for its potential applications in plant health and protection. Its complex structure and interactions with biological systems may offer new ways to enhance crop yields and resistance to diseases.
Note: The uses listed above are hypothetical and based on the general properties of the compound. Further research and development would be required to determine the specific applications and efficacy of this compound in each industry.
Check Digit Verification of cas no
The CAS Registry Mumber 18866-87-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,8,6 and 6 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 18866-87:
(7*1)+(6*8)+(5*8)+(4*6)+(3*6)+(2*8)+(1*7)=160
160 % 10 = 0
So 18866-87-0 is a valid CAS Registry Number.
InChI:InChI=1/C27H48O4/c1-16(7-6-11-25(2,3)31)19-8-9-20-24-21(15-23(30)27(19,20)5)26(4)12-10-18(28)13-17(26)14-22(24)29/h16-24,28-31H,6-15H2,1-5H3/t16-,17+,18-,19-,20+,21+,22-,23+,24+,26+,27-/m1/s1
18866-87-0Relevant articles and documents
Bile acids. LXXIII. Synthesis of analogs of 7α-hydroxy-4-cholesten-3-one as substrates for hepatic steroid 12α-hydroxylase
Joyce, Michael J.,Hiremath, S. V.,Mattammal, Michael B.,Elliott, William H.,Doisy, Edward A.
, p. 95 - 102 (1984)
Analogs of 7α-hydroxy-4-cholesten-3-one were prepared to ascertain structural features necessary for maximal activity of hepatic microsomal 12α-steroid hydroxylase.Methyl 3α,7α-dihydroxy-5β-cholane-24-carboxylate derived from chenodeoxycholic acid was oxidized at C-3 with silver carbonate/Celite.The product was hydrolyzed and dehydrogenated with SeO2 to provide 3-oxo-7α-hydroxy-4-cholene-24-carboxylic acid. 5β-Cholestane-3α,7α,25-triol and 5β-cholestane-3α,7α,12α,25-tetrol were similarly oxidized at C-3 and dehydrogenated to provide 7α,25-dihydroxy-4-cholesten-3-one and 7α,12α,25-trihydroxy-4-cholesten-3-one, respectively.The products were characterized by thin-layer and gas chromatography, ultraviolet, infrared, proton resonance and mass spectrometry.
7β-Hydroxy bile alcohols: Facile synthesis and 2D 1H NMR studies of 5β-cholestane-3α,7β,12α,25-tetrol
Dayal, Bishambar,Ertel,Padia,Rapole,Salen
, p. 409 - 414 (1997)
A rapid and easily performed procedure for the synthesis of 5β- cholestane-3α,7β,12α,25-tetrol by means of an efficient homologation sequence of the intermediate, 3α,7β,12α-triformyloxy-24-oxo-25-diazo-25- homo-5β-cholane is described. The reaction sequence involved treating the intermediate, α-diazoketone in methanol with 3% AgNO3 or Ag2O, anhydrous Na2CO3, Na2S2O3/H2O resulting in the formation of homoursocholic acid in high yield. Esterification of the homoursocholic acid in methanol containing a catalytic amount of methanesulfonic acid under microwave irradiation conditions gave methyl homoursocholate. The subsequent treatment of methyl homoursocholate with methyl magnesium iodide provided 5β- cholestane-3α,7β,12α,25-tetrol in 88% yield. The products and synthetic intermediates prepared in these studies were fully characterized by the results of 1D and 2D NMR, and high-resolution mass spectral studies. These studies will help in further investigation of the defect of cholic acid biosynthesis in patients with cerebrotendinous xanthomatosis (CTX) as well as other inborn errors of bile acid metabolism.
