188684-46-0

Basic information

• Product Name: 3-Oxo-butyric acid (1R,2S)-2-phenyl-cyclohexyl ester
• CAS NO: 188684-46-0
• Molecular Weight: 260.333
• Mol File: 188684-46-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Oxo-butyric acid (1R,2S)-2-phenyl-cyclohexyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Oxo-butyric acid (1R,2S)-2-phenyl-cyclohexyl ester(188684-46-0)
• EPA Substance Registry System: 3-Oxo-butyric acid (1R,2S)-2-phenyl-cyclohexyl ester(188684-46-0)

Safety Data

• Hazardous Substances Data: 188684-46-0(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 98919-68-7 (1R,2S)-trans-2-phenylcyclohexanol 
• 75-36-5 acetyl chloride 

Downstream Products

• 188663-02-7 2-Diazo-propionic acid (1R,2S)-2-phenyl-cyclohexyl ester 
• 200569-88-6 (E)-2-(1,3-Dioxo-1,3-dihydro-isoindol-2-ylsulfanyl)-3-hydroxy-but-2-enoic acid (1R,2S)-2-phenyl-cyclohexyl ester 

Relevant articles and documents

α,α'-Dioxothiones part 2. Asymmetric Diels-Alder reactions of chiral non-racemic α,α'-dioxothiones

Chiral non-raemic α,α'-dioxothiones 2a-g and 17 are obtained from chiral β-ketoesters using the phthalimidesulfenyl chloride 1 as key reagent. The ability of these thiones to discriminate between the enantiotopic faces of several dienophiles has been evaluated. The best diastereoisomeric excesses (67-80%) were obtained when the a-acyl thiones were involved as electron-poor dienes in inverse electron demand Diels-Alder reactions with electron-rich styrenes as dienophiles. The possibility to obtain thiones bearing two chiral groups as well as the reactions where the a-acyl thiones 2 participate as dienophiles are also shown.