1887-73-6

Basic information

• Product Name: Benzene, 1,2,4,5-tetrafluoro-3-methoxy-6-nitro-
• CAS NO: 1887-73-6
• Molecular Formula: C7H3F4NO3
• Molecular Weight: 225.099
• Mol File: 1887-73-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzene, 1,2,4,5-tetrafluoro-3-methoxy-6-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,2,4,5-tetrafluoro-3-methoxy-6-nitro-(1887-73-6)
• EPA Substance Registry System: Benzene, 1,2,4,5-tetrafluoro-3-methoxy-6-nitro-(1887-73-6)

Safety Data

• Hazardous Substances Data: 1887-73-6(Hazardous Substances Data)

Usage

General Description

Benzene, 1,2,4,5-tetrafluoro-3-methoxy-6-nitro- is a chemical compound with the molecular formula C6H2F4NO3O. It is a nitro-based compound that contains four fluorine atoms and one methoxy group attached to the benzene ring. This chemical is used in the manufacturing of various products, such as pharmaceuticals and agrochemicals. It is also used as a building block in organic synthesis and as a solvent in various chemical reactions. Benzene, 1,2,4,5-tetrafluoro-3-methoxy-6-nitro- is known for its high reactivity and is considered to be hazardous to human health and the environment.

Upstream product

• 880-78-4 pentafluoronitrobenzen 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 1825-61-2 Trimethylmethoxysilane 
• 124-41-4 sodium methylate 
• 67-56-1 methanol 
• 2324-98-3 2,3,5,6-tetrafluoroanisole 

Downstream Products

• 31639-88-0 3-CH₃O-6-NO₂-C₆F₃N(H)C₆F₅ 
• 14851-30-0 2-Methylamino-4-methoxy-3,4,6-trifluor-nitrobenzol 
• 14851-31-1 2-Dimethylamino-4-methoxy-3,5,6-trifluor-nitrobenzol 
• 14851-29-7 2-Amino-4-methoxy-3,4,6-trifluor-nitrobenzol 
• 3480-60-2 2,4-Dimethoxy-3,5,6-trifluoronitrobenzene 
• 1643-71-6 2,3,5,6-tetrafluoro-4-methoxyaniline 
• 2010-70-0 2,3,5,6-tetrafluoro-4-methoxyacetanilide 

Relevant articles and documents

Reductively activated "Polar" nucleophilic aromatic substitution. III - The reactions of polyfluoronitrobenzenes with methanol

The nucleophilic aromatic substitution reactions of pentafluoronitrobenzene (PFNB) and 2,3,4,5-tetrafluoronitrobenzene with methanol are both reductively activated. However, the first one is sensitive to the presence of radical scavengers but the second i

Mechanism of Oxidative Activation of Fluorinated Aromatic Compounds by N-Bridged Diiron-Phthalocyanine: What Determines the Reactivity?

The biodegradation of compounds with C?F bonds is challenging due to the fact that these bonds are stronger than the C?H bond in methane. In this work, results on the unprecedented reactivity of a biomimetic model complex that contains an N-bridged diiron-phthalocyanine are presented; this model complex is shown to react with perfluorinated arenes under addition of H2O2 effectively. To get mechanistic insight into this unusual reactivity, detailed density functional theory calculations on the mechanism of C6F6 activation by an iron(IV)-oxo active species of the N-bridged diiron phthalocyanine system were performed. Our studies show that the reaction proceeds through a rate-determining electrophilic C?O addition reaction followed by a 1,2-fluoride shift to give the ketone product, which can further rearrange to the phenol. A thermochemical analysis shows that the weakest C?F bond is the aliphatic C?F bond in the ketone intermediate. The oxidative defluorination of perfluoroaromatics is demonstrated to proceed through a completely different mechanism compared to that of aromatic C?H hydroxylation by iron(IV)-oxo intermediates such as cytochrome P450 Compound I.

Fluorine-containing phenylmaleimide derivative, polymer, chemically amplified resist composition, and method for pattern formation using the composition

A fluorine-containing phenylmaleimide derivative having a specific structure. A polymer obtained by polymerizing monomers containing the derivative. A polymer containing a specific structural unit and having a weight-average molecular weight of 2,000 to 2