188885-56-5Relevant articles and documents
Alkylation of 4,5-Dichloropyridazin-6-one with α,ω-Dibromoalkanes or 4,5-Dichloro-1-(ω-bromoalkyl)pyridazin-6-ones
Kim, Sung-Kyu,Cho, Su-Dong,Kweon, Deok-Heon,Yoon, Yong-Jin,Kim, Jung-Ho,Heo, Jung-Nyoung
, p. 209 - 214 (2007/10/03)
Alkylations of 4,5-dichloropyridazin-6-one (1) with dibromoalkanes 2 or 3 in the presence of potassium carbonate or tetrabutylammonium bromide/potassium hydroxide were investigated under restricted condition.Reactions of 1 with 2 or 3, except for 2b and 3b, in the presence of potassium carbonate or tetrabutylammonium bromide/potassium hydroxide gave only the N-alkylation products 3 and/or 4.Alkylation of 1 with 2b or 3b in the presence of potassium carbonate yielded the N-alkylation products 3b and/or 4b and the O-alkylation product 5 as the main product, whereas treatment of 1 with 2b or 3b in the presence of tetrabutylammonium bromide/potassium hydroxide afforded selectively the N-alkylation products 3b and/or 4b.