189074-86-0Relevant articles and documents
Regioselective enzymatic acylation of β-L-2′-deoxynucleosides: Application in resolution of β-D/L-2′-deoxynucleosides
Garcia, Javier,Fernandez, Susana,Ferrero, Miguel,Sanghvi, Yogesh S.,Gotor, Vicente
, p. 3759 - 3762 (2004)
(Chemical Equation Presented) A practical synthesis of β-L-3′- and β-L-5′-O-levulinyl-2′-deoxynucleosides has been described for the first time through enzymatic acylation and/or hydrolysis processes. It is noteworthy that the different behavior exhibited by Pseudomonas cepacia lipase in the acylation of D- and L-nucleosides allows the parallel kinetic resolution of D/L-nucleosides.