18908-55-9 Usage
General Description
3-[cyano(phenyl)methyl]benzoic acid is a chemical compound with the molecular formula C15H11NO2. It is a white to light yellow crystalline powder that is slightly soluble in water. 3-[cyano(phenyl)methyl]benzoic acid is a derivative of benzoic acid and has a cyano group attached to the benzene ring. It is commonly used as an intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds. The cyano group and phenylmethyl group in the structure make it a valuable building block for creating more complex molecules in the pharmaceutical and agrochemical industries. Additionally, it also has potential applications in research and development for its ability to undergo various chemical reactions, making it a versatile compound with diverse uses.
Check Digit Verification of cas no
The CAS Registry Mumber 18908-55-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,8,9,0 and 8 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 18908-55:
(7*1)+(6*8)+(5*9)+(4*0)+(3*8)+(2*5)+(1*5)=139
139 % 10 = 9
So 18908-55-9 is a valid CAS Registry Number.
18908-55-9Relevant articles and documents
Preparation of 2-Cyanobenzoic Acids from the Reaction of Bromobenzoic Acids with Arylacetonitriles and LDA
Wang, Anlai,Maguire, John A.,Biehl, Ed
, p. 2451 - 2455 (2007/10/03)
The reaction of various bromobenzoic acids 1 with arylacetonitriles 3 in the presence of LDA at -70°C gave predominantly 2-cyanobenzoic acids 4 plus minor amounts of 3-(arylcyanomethyl)-benzoic acids 5 and debrominated benzoic acids 6. The reaction is thought to proceed through a benzyne-3-carboxylate intermediate 2, which is formed at -70°C upon the addition of the arylacetonitrile 3 to a solution of the appropriate lithium halobenzoate and excess LDA. The base-initiated generation of an aryne intermediate from a haloarene at such low temperatures is unprecedented. To confirm the orientation of the cyano and carboxylic acid groups, 4-methoxy-2-cyanobenzoic acid (4f) was converted to the corresponding anhydride (8) via phthalic acid (7) and to 3,3-dimethyl- and 3,3-di-n-butyl-2,3-dihydro-5-methoxy-4-(4-methoxyphenyl)-methyl-1H-isoindol-1- ones (9).
